Bianjiang Zhang, Jianchun Zhang, Xiaoyu Shi, Jian Yang
College of Physical Education and Health, East China Normal University, Shanghai, 200241, China.
College of Physical Education, China University of Mining and Technology, Xuzhou City, Jiangsu Province, China.
BMC Psychiatry. 2025 Feb 26;25(1):178. doi: 10.1186/s12888-025-06620-x.
Post-traumatic stress disorder (PTSD) is a potentially disabling condition that can lead to long-term impairments, with a significant proportion of adolescents being affected by trauma. Studies have suggested that trauma-focused cognitive behavioral therapy (TF-CBT) is an effective treatment for PTSD in adolescents, however, little is known about the relative advantages of different mind-body interventions. The network meta-analysis aims to evaluate and compare the efficacy of various mind-body interventions in alleviating PTSD symptoms in adolescents.
A systematic search was conducted across multiple databases including PubMed, Embase, Web of Science, Scopus, The Cochrane Library, CNKI, WFDSP, and VIP databases. Randomized controlled trials (RCTs) evaluating the effects of mind-body interventions on PTSD in adolescents were included. A network meta-analysis (NMA) was conducted to evaluate the effectiveness of various mind-body intervention therapies using the Surface Under the Cumulative Ranking curve (SUCRA). SUCRA calculates the mean of the cumulative percent area under the curve for each therapy, providing a comprehensive ranking of treatment efficacy. The primary outcomes measured were changes in PTSD symptom scores post-treatment and at follow-ups ranging from 1 to 12 months.
A total of 20 studies involving 5 interventions and 2085 adolescents were included in the analysis. No inconsistencies were found between direct and indirect evidence. TF-CBT consistently demonstrated the most significant effect in reducing PTSD symptoms compared to routine care and no-treatment groups. The ranking of intervention efficacy from highest to lowest was as follows: TF-CBT (SUCRA = 87.3%), meditation, CBT, yoga combined with meditation and mindfulness (SUCRA = 32.3%). Due to limited evidence, the follow-up results for PTSD symptom changes remained inconclusive.
Five mind-body interventions were found to be effective in treating PTSD symptoms in adolescents, with TF-CBT emerging as the most effective treatment. Findings suggest that yoga combined with meditation and mindfulness may have promising effects, however, further research is needed to confirm these results due to the limited evidence available.
创伤后应激障碍（PTSD）是一种可能导致残疾的疾病，可导致长期损害，相当一部分青少年受到创伤影响。研究表明，以创伤为重点的认知行为疗法（TF-CBT）是治疗青少年PTSD的有效方法，然而，对于不同身心干预措施的相对优势知之甚少。网络荟萃分析旨在评估和比较各种身心干预措施在减轻青少年PTSD症状方面的疗效。
在多个数据库中进行系统检索，包括PubMed、Embase、科学网、Scopus、考克兰图书馆、中国知网、万方数据和维普数据库。纳入评估身心干预措施对青少年PTSD影响的随机对照试验（RCT）。使用累积排名曲线下面积（SUCRA）进行网络荟萃分析（NMA），以评估各种身心干预疗法的有效性。SUCRA计算每种疗法曲线下累积百分比面积的平均值，提供治疗效果的综合排名。测量的主要结局是治疗后以及1至12个月随访时PTSD症状评分的变化。
分析共纳入20项研究，涉及5种干预措施和2085名青少年。直接证据和间接证据之间未发现不一致之处。与常规护理组和未治疗组相比，TF-CBT在减轻PTSD症状方面始终显示出最显著的效果。干预效果从高到低的排名如下：TF-CBT（SUCRA = 87.3%）、冥想、认知行为疗法（CBT）、瑜伽结合冥想和正念（SUCRA = 32.3%）。由于证据有限，PTSD症状变化的随访结果仍无定论。
发现五种身心干预措施对治疗青少年PTSD症状有效，其中TF-CBT是最有效的治疗方法。研究结果表明，瑜伽结合冥想和正念可能有显著效果，然而，由于现有证据有限，需要进一步研究来证实这些结果。
