Nussenblatt R B, Palestine A G, Chan C C, Roberge F
Ophthalmology. 1985 Apr;92(4):467-71. doi: 10.1016/s0161-6420(85)34001-0.
Standardization of observations is recognized as fundamental to clinical research. The methodology for the evaluation of anterior segment inflammatory disease has become well accepted, while the ocular inflammatory standardization of the posterior segment has not been so well described or accepted. A system for the evaluation of vitreal inflammatory activity in patients with intermediate and posterior uveitis is presented. A series of photographs representing various degrees of fundus vitreal haze is depicted. The observer examines the eye with an indirect ophthalmoscope, then chooses the photograph which most closely simulates what is being seen. This technique is rapid and its reproducibility is helpful in standardizing clinical observations.
观察的标准化被认为是临床研究的基础。前段炎症性疾病的评估方法已被广泛接受,而后段眼部炎症的标准化描述和接受程度则没那么高。本文介绍了一种评估中间葡萄膜炎和后葡萄膜炎患者玻璃体炎症活动的系统。展示了一系列代表不同程度眼底玻璃体混浊的照片。观察者用间接检眼镜检查眼睛,然后选择最能模拟所见情况的照片。这项技术快速,其可重复性有助于临床观察的标准化。