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肺动静脉畸形导致肺隔离症和纵隔梗死:一例报告。

Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report.

作者信息

Griffo Raffaella, Klotz Laura V, Brendel Lena, Rösch Romina, Niedermaier Benedikt, Schlamp Kai, Kriegsmann Mark, Eichhorn Martin M, Winter Hauke

机构信息

Thoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Translational Lung Research Center (TLRC), Heidelberg, Germany.

出版信息

Front Med (Lausanne). 2025 Feb 11;12:1490820. doi: 10.3389/fmed.2025.1490820. eCollection 2025.

Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The complexity of the pathology lies not only in the variety of its manifestations, but also in the choice of the most appropriate and effective treatment. We present a case of a complex PAVM associated with a persistent foramen ovale, with stroke as the onset symptom. Despite timely multidisciplinary treatment of the malformation, a potentially fatal pulmonary complication occurred, highlighting the critical importance of early, interdisciplinary management and ongoing follow-up of PAVMs, particularly in preventing life-threatening outcomes.

摘要

肺动静脉畸形(PAVM)是一种罕见的肺部血管畸形。肺动脉与肺静脉直接相通是其决定性特征,这使得静脉血绕过肺毛细血管系统,无法进行有效的氧合过程。该病理状况的复杂性不仅在于其表现形式多样,还在于选择最合适、最有效的治疗方法。我们报告一例与持续性卵圆孔未闭相关的复杂PAVM病例,以中风为首发症状。尽管对该畸形进行了及时的多学科治疗,但仍发生了潜在致命的肺部并发症,这凸显了对PAVM进行早期、跨学科管理及持续随访的至关重要性,尤其是在预防危及生命的后果方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f4b/11850261/56f9ca5c3c43/fmed-12-1490820-g0001.jpg

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