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西班牙关于重症监护病房中气道清除技术对严重急性呼吸综合征冠状病毒2(新冠病毒)疗效的经验:一篇社论及病例报告

Spanish experience on the efficacy of airways clearance techniques in SARS-CoV-2 (COVID-19) at intensive care unit: An editorial and case report.

作者信息

Sánchez Romero Eleuterio A, Alonso Pérez José Luis, Vinuesa Suárez Inmaculada, Corbellini Camilo, Villafañe Jorge Hugo

机构信息

Musculoskeletal Pain and Motor Control Research Group, Faculty of Sport Sciences, Universidad Europea de Madrid, Madrid, Spain.

Department of Physiotherapy, Faculty of Sport Sciences, Universidad Europea de Madrid, Madrid, Spain.

出版信息

SAGE Open Med Case Rep. 2022 Jul 18;10:2050313X221112507. doi: 10.1177/2050313X221112507. eCollection 2022.

Abstract

COVID-19 pandemic did not impact all countries in the same way, and in Spain, the percentage of intensive care unit (ICU) and the mortality rate patients has been very high. The present work aims to present the first case of the new Coronavirus-2019 (COVID-19) on March 23, 2020, in Tenerife, Canary Islands, Spain, of a patient on Invasive Mechanical Ventilation (IMV) affected by acute pneumonia which was treated by airway clearance techniques (ACT) thinking that she was not infected with COVID-19, since the first polymerase chain reaction (PCR) test was negative. The subject presented septic shock, hypoxemic encephalopathy, and seizures. Right lung base consolidation and pleural effusion were visible in the echography. The thorax x-ray presented subcutaneous emphysema and pleural effusion in the right base and an alveolar-interstitial opacity pattern in the left. Bilateral crackles and rhonchus were evident in the right lung during the lung auscultation. The airway clearance protocol comprises Cough Assist (CA) and chest compressions. The variables collected were the ventilatory parameters, blood gas analysis, and thorax x-ray description. ACT protocol improves gas exchange and expands consolidated lung areas in this atypical clinical case presented. At that time, this type of treatment was not performed on patients affected by COVID-19, and the next day we found that the patient had improved, coinciding with the second PCR test, which was positive.

摘要

新冠疫情对各国的影响不尽相同,在西班牙,重症监护病房(ICU)收治患者的比例和死亡率一直很高。本研究旨在介绍2020年3月23日在西班牙加那利群岛特内里费岛出现的首例新型冠状病毒2019(COVID-19)病例。该患者因急性肺炎接受有创机械通气(IMV)治疗,最初认为未感染COVID-19,因为首次聚合酶链反应(PCR)检测呈阴性,遂采用气道廓清技术(ACT)进行治疗。该患者出现感染性休克、低氧性脑病和癫痫发作。超声检查可见右肺底部实变和胸腔积液。胸部X光显示右肺底部皮下气肿和胸腔积液,左肺呈现肺泡间质模糊影。肺部听诊时右肺可闻及双侧湿啰音和哮鸣音。气道廓清方案包括咳嗽辅助(CA)和胸部按压。收集的变量包括通气参数、血气分析和胸部X光描述。在这个非典型临床病例中,ACT方案改善了气体交换并扩大了实变的肺区。当时,这种治疗方法并未应用于COVID-19患者,第二天我们发现患者病情有所改善,同时第二次PCR检测呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b806/9297451/1a3575127bc0/10.1177_2050313X221112507-fig1.jpg

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