This study investigates the interactions between climate change and human health with a particular focus on Qatar, using the DPSIR (Driving Forces, Pressures, States, Impacts, Responses) framework. Key drivers, including economic development and population growth, contribute to increased greenhouse gas (GHG) emissions, exerting pressure on Qatar's climate through rising temperatures and altered precipitation patterns, as modeled by the MIT Regional Climate Model (MRCM). The findings reveal critical gaps in understanding the state of climate-health interactions, including insufficient disease data, incomplete climate-health linkages, and significant research gaps. These limitations hinder targeted responses to climate-sensitive diseases, which have shown an increase over the years. The study identifies the pathways through which climatic shifts contribute to immediate health risks, such as heat-related illnesses and respiratory conditions, as well as long-term impacts, including chronic diseases and mental health challenges. Despite Qatar's efforts through national and international strategies, the DPSIR analysis highlights the urgent need for enhanced research, improved data collection, and tailored actions to address these challenges. Strengthened adaptation, resilience-building, and emission reduction strategies remain essential for safeguarding public health in the face of accelerating climate change.