Izquierdo-Condoy Juan S, Gualpa Álvarez Fernando, Morales-Lapo Estefania, Arias Calvache Washington David, Bermúdez Moreira Jessica, Quinga-Chiguano Katherine M, Ortiz-Prado Esteban
One Health Research Group, Universidad de las Américas, Quito, Ecuador.
Departamento de Neumología, Hospital Quito No.1 de la Policía Nacional, Quito, Ecuador.
Int J Chron Obstruct Pulmon Dis. 2025 Feb 21;20:399-410. doi: 10.2147/COPD.S493992. eCollection 2025.
Chronic Obstructive Pulmonary Disease (COPD), the third leading cause of death globally, poses a significant public health burden. Despite its high prevalence, underdiagnosis and poor treatment adherence remain major challenges, contributing to increased hospitalization and mortality.
This study aimed to assess adherence to inhalation therapy among COPD patients treated at a specialty hospital in Quito, Ecuador.
A cross-sectional study was conducted on 85 patients diagnosed with COPD at a tertiary hospital in Quito. Data was collected through face-to-face surveys, utilizing the TAI-10 questionnaire to assess treatment adherence, along with demographic and clinical characteristics of the patients.
Among the participants, 34.1% demonstrated good adherence to inhalation therapy, while 32.9% exhibited intermediate adherence, and 32.9% were non-adherent. The majority were older adults aged ≥76 years (67.1%) with a high prevalence of comorbidities (91.8%), particularly hypertension (58.8%). Non-adherence was primarily associated with forgetfulness and financial constraints. Higher BMI was significantly linked to better adherence, with obese patients showing higher odds of intermediate (OR=7.228, 95% CI 1.866-27.996) and good adherence (OR=9.966, 95% CI 2.538-39.139).
Approximately one-third of COPD patients in Ecuador demonstrate good adherence to inhalation therapy, while similar proportions show intermediate or poor adherence. Predominantly older adults and retirees with comorbidities, the population identified forgetfulness and financial constraints as key barriers. These findings emphasize the need for enhanced patient education, regular follow-ups, and tailored support for vulnerable groups.
慢性阻塞性肺疾病(COPD)是全球第三大死因,造成了巨大的公共卫生负担。尽管其患病率很高,但诊断不足和治疗依从性差仍然是主要挑战,导致住院率和死亡率上升。
本研究旨在评估在厄瓜多尔基多一家专科医院接受治疗的COPD患者对吸入疗法的依从性。
对基多一家三级医院诊断为COPD的85名患者进行了横断面研究。通过面对面调查收集数据,使用TAI-10问卷评估治疗依从性以及患者的人口统计学和临床特征。
在参与者中,34.1%对吸入疗法表现出良好依从性,32.9%表现出中等依从性,32.9%不依从。大多数是年龄≥76岁的老年人(67.1%),合并症患病率高(91.8%),尤其是高血压(58.8%)。不依从主要与健忘和经济限制有关。较高的体重指数与更好的依从性显著相关,肥胖患者表现出中等依从性(OR=7.228,95%CI 1.866-27.996)和良好依从性(OR=9.966,95%CI 2.538-39.139)的几率更高。
在厄瓜多尔,约三分之一的COPD患者对吸入疗法表现出良好依从性,而相似比例的患者表现出中等或差的依从性。主要是患有合并症的老年人和退休人员,该人群将健忘和经济限制视为关键障碍。这些发现强调需要加强患者教育、定期随访以及为弱势群体提供针对性支持。