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追踪蛋白质病在阿尔茨海默病临床前阶段的神经生理效应。

Tracking the neurophysiological effects of proteinopathy into the pre-clinical stage of Alzheimer's disease.

作者信息

Wiesman Alex I, Flores-Alonso Santiago I

机构信息

Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada, BC V3L 1B3.

出版信息

Brain Commun. 2025 Feb 11;7(1):fcaf069. doi: 10.1093/braincomms/fcaf069. eCollection 2025.

Abstract

This scientific commentary refers to 'Amyloid-β deposition predicts oscillatory slowing of magnetoencephalography signals and a reduction of functional connectivity over time in cognitively unimpaired adults', by Scheijbeler . (https://doi.org/10.1093/braincomms/fcaf018).

摘要

这篇科学评论参考了谢伊贝勒的《淀粉样β蛋白沉积预测认知未受损成年人的脑磁图信号振荡减慢及功能连接随时间的减少》(https://doi.org/10.1093/braincomms/fcaf018)。

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本文引用的文献

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Synergistic association of Aβ and tau pathology with cortical neurophysiology and cognitive decline in asymptomatic older adults.
Nat Neurosci. 2024 Nov;27(11):2130-2137. doi: 10.1038/s41593-024-01763-8. Epub 2024 Sep 18.
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Neurochemical organization of cortical proteinopathy and neurophysiology along the Alzheimer's disease continuum.
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Spatially resolved neural slowing predicts impairment and amyloid burden in Alzheimer's disease.
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