磷酸化tau蛋白是阿尔茨海默病突触病理学的良好生物标志物吗？
Is phosphorylated tau a good biomarker of synapse pathology in Alzheimer's disease?
作者信息
Saura Carlos A, Parra-Damas Arnaldo
机构信息
Departament de Bioquímica i Biologia Molecular, Institut de Neurociències, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra 08193, Spain.
Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.
出版信息
Brain Commun. 2023 Apr 27;5(3):fcad142. doi: 10.1093/braincomms/fcad142. eCollection 2023.
This scientific commentary refers to 'Distinct brain pathologies associated with Alzheimer's disease biomarker-related phospho-tau 181 and phospho-tau 217 in knock-in mouse models of amyloid-β amyloidosis' by Hirota (https://doi.org/10.1093/braincomms/fcac286) and 'Predictive blood biomarkers and brain changes associated with age-related cognitive decline' by Saunders . (https://doi.org/10.1093/braincomms/fcad113).
本科学评论参考了广田的《淀粉样β淀粉样变性基因敲入小鼠模型中与阿尔茨海默病生物标志物相关的磷酸化tau 181和磷酸化tau 217相关的不同脑病理学》（https://doi.org/10.1093/braincomms/fcac286）以及桑德斯的《与年龄相关的认知衰退相关的预测性血液生物标志物和脑变化》（https://doi.org/10.1093/braincomms/fcad113）。
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