Majewska Oliwia, Pach Radosław, Brzewski Paweł, Kulig Jan, Kulig Piotr
Andrzej Frycz Modrzewski Krakow University Faculty of Medicine and Health Sciences, Krakow, Poland.
Jagiellonian University Medical College, Krakow, Poland.
In Vivo. 2025 Mar-Apr;39(2):1112-1121. doi: 10.21873/invivo.13916.
BACKGROUND/AIM: TNM stage is crucial for patients with gastric cancer because curative resection and treatment are only possible in early TNM stages. Therefore, our objective was to assess the association of clinicopathological features with TNM stage in such patients.
The association of age, sex, tumor location and Lauren type with TNM stage was analyzed in 910 patients with gastric cancer.
Age, sex, and tumor location did not have any association with TNM stage in univariate nor multivariate analyses (>0.05). However, compared to the diffuse and mixed types, the intestinal type (as defined by the Lauren classification) presented lower T stage of gastric cancer in the chi-squared test (<0.001) and this association was confirmed in the multinominal log normal model (=0.001).
The histological Lauren type of gastric cancer is associated with lower TNM T stage.
背景/目的：TNM分期对于胃癌患者至关重要，因为只有在TNM早期阶段才有可能进行根治性切除和治疗。因此，我们的目的是评估此类患者的临床病理特征与TNM分期之间的关联。
分析了910例胃癌患者的年龄、性别、肿瘤位置和劳伦分型与TNM分期之间的关联。
在单因素和多因素分析中，年龄、性别和肿瘤位置与TNM分期均无关联（>0.05）。然而，在卡方检验中，与弥漫型和混合型相比，肠型（根据劳伦分类定义）的胃癌T分期较低（<0.001），并且在多项对数正态模型中证实了这种关联（=0.001）。
胃癌的组织学劳伦分型与较低的TNM T分期相关。
