Butera P C, Czaja J A
Physiol Behav. 1985 Feb;34(2):319-21. doi: 10.1016/0031-9384(85)90123-4.
The ability of dihydrotestosterone (DHT) to maintain androgen-sensitive target tissue and masculine sexual behavior was examined in castrated male rats and guinea pigs. Silastic capsules filled with DHT amd implanted subdermally at the time of castration were found to stimulate epididymal tissue in a dose-dependent manner in both species. However, differences were found in the behavioral effectiveness of this steroid. Capsules containing sufficient DHT to maintain peripheral structures were effective in maintaining copulatory behavior of castrated guinea pigs, but not of the similarly treated rats.
在去势的雄性大鼠和豚鼠中研究了二氢睾酮(DHT)维持雄激素敏感靶组织和雄性性行为的能力。在去势时皮下植入填充有DHT的硅橡胶胶囊,结果发现其在两个物种中均以剂量依赖性方式刺激附睾组织。然而,发现这种类固醇在行为效应方面存在差异。含有足以维持外周结构的DHT的胶囊能有效维持去势豚鼠的交配行为,但对同样处理的大鼠则无效。