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抗MDA-5阳性无肌病性皮肌炎的多系统并发症及快速病情恶化:一例病例研究

Multisystemic Complications and Rapid Decline in Anti-MDA-5 Positive Amyopathic Dermatomyositis: A Case Study.

作者信息

Prajapati Hem, Chauhan Yesha R, Patel Sahaj Y, Parmar Ajay C, Shaikhjiwala Tasin Mohammedyakub

机构信息

Intern, Government Medical College Vadodara India.

Intern at Medical College Baroda, SSGH Vadodara India.

出版信息

Clin Case Rep. 2025 Feb 25;13(3):e70261. doi: 10.1002/ccr3.70261. eCollection 2025 Mar.

Abstract

Anti-MDA-5 positive amyopathic dermatomyositis (CADM) can lead to rapid multisystemic complications, including severe interstitial lung disease (ILD). This case, involving a 60-year-old female with worsening skin lesions and ILD, demonstrates the disease's aggressive nature, highlighting the need for early diagnosis and comprehensive immunosuppressive therapy to improve patient outcomes.

摘要

抗黑色素瘤分化相关蛋白5(MDA-5)阳性无肌病性皮肌炎(CADM)可导致快速的多系统并发症,包括严重的间质性肺病(ILD)。本病例为一名60岁女性,皮肤病变和ILD病情恶化,显示了该疾病的侵袭性,强调了早期诊断和全面免疫抑制治疗以改善患者预后的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e9b/11860283/1874fd610544/CCR3-13-e70261-g002.jpg

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