Itano M, Nussbaum E, Symons J L
Respiration. 1985;47(3):220-4. doi: 10.1159/000194773.
Presented here are chloride results obtained by direct titration of undiluted sweat collected with the Webster Sweat Collection System. Six hundred and thirty-two sweat chloride results were reported on 604 patients. Thirty-six of thirty-nine sweat chloride results of 60 mM or greater were from patients with cystic fibrosis. Three results (61, 63 and 64 mM) were from a 12-year-old female who had one episode of rectal prolapse but after one year does not have clinical evidence of cystic fibrosis. There was one patient with a cystic fibrosis variant with intermediate range sweat chloride. All others in the intermediate range (40-59 mM) did not have cystic fibrosis. One patient with a sweat chloride reported of less than 40 mM was subsequently found to have cystic fibrosis at another institution.
这里展示的是通过直接滴定用韦伯斯特汗液采集系统采集的未稀释汗液所获得的氯化物检测结果。对604例患者报告了632次汗液氯化物检测结果。39次汗液氯化物检测结果中,有36次大于或等于60 mM,这些结果来自患有囊性纤维化的患者。3次检测结果(61、63和64 mM)来自一名12岁女性,该女性有过一次直肠脱垂,但一年后没有囊性纤维化的临床证据。有一名患有囊性纤维化变异型的患者,其汗液氯化物处于中等范围。所有其他处于中等范围(40 - 59 mM)的患者均没有囊性纤维化。有一名汗液氯化物检测结果小于40 mM的患者,后来在另一家机构被发现患有囊性纤维化。