Fernández-González Adriana M, López-Pérez Andrés M, Herrera-Mares Angel, Chaves Andrea, Ramírez-Corona Fabiola, Suzán Gerardo
Departamento de Etología, Fauna Silvestre y Animales de Laboratorio, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, México.
Red de Biología y Conservación de Vertebrados, Instituto de Ecología A.C., Veracruz, México.
Epidemiol Infect. 2025 Feb 28;153:e42. doi: 10.1017/S0950268825000238.
is a widely distributed Gram-negative bacterium that includes species that are capable of causing illness in humans. Rodents represent one of the main reservoirs of zoonotic pathogens, and monitoring their populations can provide valuable insights into human health. We conducted a surveillance study of rodents from two north-western states of Mexico (Baja California and Chihuahua) to investigate the prevalence and genetic diversity of by polymerase chain reaction (PCR) amplification and sequencing of the citrate synthase () gene. A total of 586 rodents belonging to 28 species were captured, and 408 were tested for spp. The overall spp. prevalence was 39.71%. The prevalence found in Chihuahua was higher (42.80%) than in Baja California (32.52%), and rodents such as , , , and had the highest prevalence. The sequences revealed seven genetic variants, some of which were obtained from and rodents and were associated with species of human health concern, such as and subsp. In addition, a sequence obtained from a was clustered with Bartonella rudakovii, a previously unreported association. This study provides valuable data and new insight into the -hosts interactions in rodent species in north-western Mexico.
是一种广泛分布的革兰氏阴性菌，其中包括能够导致人类患病的物种。啮齿动物是人畜共患病原体的主要宿主之一，监测它们的种群数量可以为人类健康提供有价值的见解。我们对墨西哥西北部两个州（下加利福尼亚州和奇瓦瓦州）的啮齿动物进行了一项监测研究，通过聚合酶链反应（PCR）扩增和柠檬酸合酶（）基因测序来调查其流行率和遗传多样性。总共捕获了属于28个物种的586只啮齿动物，并对其中408只进行了 spp.检测。spp.的总体流行率为39.71%。在奇瓦瓦州发现的流行率（42.80%）高于下加利福尼亚州（32.52%），并且诸如、、和等啮齿动物的流行率最高。的序列揭示了七个遗传变体，其中一些是从和啮齿动物中获得的，并且与人类健康相关的物种有关，例如和亚种。此外，从一只获得的一个序列与鲁氏巴尔通体（Bartonella rudakovii）聚在一起，这是一种以前未报道过的关联。这项研究为墨西哥西北部啮齿动物物种中的-宿主相互作用提供了有价值的数据和新见解。
