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人类巴尔通体病:一个未得到充分重视的公共卫生问题?

Human Bartonellosis: An Underappreciated Public Health Problem?

作者信息

Cheslock Mercedes A, Embers Monica E

机构信息

Division of Immunology, Tulane National Primate Research Center, Tulane University Health Sciences, Covington, LA 70433, USA.

出版信息

Trop Med Infect Dis. 2019 Apr 19;4(2):69. doi: 10.3390/tropicalmed4020069.

Abstract

spp. bacteria can be found around the globe and are the causative agents of multiple human diseases. The most well-known infection is called cat-scratch disease, which causes mild lymphadenopathy and fever. As our knowledge of these bacteria grows, new presentations of the disease have been recognized, with serious manifestations. Not only has more severe disease been associated with these bacteria but also species have been discovered in a wide range of mammals, and the pathogens' DNA can be found in multiple vectors. This review will focus on some common mammalian reservoirs as well as the suspected vectors in relation to the disease transmission and prevalence. Understanding the complex interactions between these bacteria, their vectors, and their reservoirs, as well as the breadth of infection by around the world will help to assess the impact of Bartonellosis on public health.

摘要

某些细菌种类在全球范围内都能找到,并且是多种人类疾病的病原体。最广为人知的感染是猫抓病,它会引起轻度淋巴结病和发热。随着我们对这些细菌的了解不断增加,该疾病出现了新的表现形式,包括严重的症状。这些细菌不仅与更严重的疾病有关,而且在多种哺乳动物中都发现了相关菌种,并且病原体的DNA可以在多种媒介中找到。本综述将重点关注一些常见的哺乳动物宿主以及与疾病传播和流行相关的疑似媒介。了解这些细菌、它们的媒介和宿主之间的复杂相互作用,以及世界各地该细菌感染的广度,将有助于评估巴尔通体病对公共卫生的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab13/6630881/3835e924e0d3/tropicalmed-04-00069-g001.jpg

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