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约旦河西岸巴勒斯坦男性中苯丙胺类兴奋剂(ATS)的使用及其与同时使用苯二氮卓类、巴比妥类药物和四氢大麻酚的关联:一项横断面研究。

Amphetamine-type stimulant (ATS) use and association with concurrent use of benzodiazepines, barbiturates and THC in the West Bank among male Palestinians: a cross-sectional study.

作者信息

Damiri Basma, Mousa Adnan, Helou Maroun Amin

机构信息

Drugs and Toxicology, An-Najah National University Faculty of Medicine and Health Sciences, Nablus, Palestine, State of.

Medicine, An-Najah National University Faculty of Medicine and Health Sciences, Nablus, Palestine, State of.

出版信息

BMJ Public Health. 2023 Dec 22;1(1):e000537. doi: 10.1136/bmjph-2023-000537. eCollection 2023 Nov.

Abstract

INTRODUCTION

Amphetamine-type stimulants (ATSs) are becoming a growing concern in the West Bank. Despite the focus on marijuana, statistics show that ATS seizures and clandestine laboratories indicate increased use of this highly addictive chemical among Palestinians. Shifting from marijuana to ATS can have severe clinical and social consequences, yet insufficient studies have been conducted. Our study aimed to evaluate the prevalence of ATS use and its correlation with other drug use in male Palestinians living in the northern West Bank.

METHODS

A cross-sectional study was conducted among Palestinian men aged ≥18 years from the north of the West Bank in 2022-2023. A self-administered questionnaire and urine analysis test were used to determine drug use. ATS users in this study tested positive for at least one of the following: amphetamines, ecstasy or methamphetamines.

RESULTS

Out of 787 participants, 129 (16.4%) were drug users. The prevalence of drug use among drug users was as follows: benzodiazepines (55.8%), amphetamines (41.1%), tetrahydrocannabinol (THC) (38.8%), methamphetamines (38.0%), barbiturates (9.3%), phencyclidine (1.6%) and ATS (48.8%); 84.1% were amphetamine and 77.7% were methamphetamine users. Most ATS users (68.3%) were polydrug users; 57.1% were benzodiazepine, 30.2% were THC and 12.7% were barbiturate users. The adjusted binary logistic regression revealed that ATS users were more likely to be benzodiazepine (OR=11.059, p<0.001), THC (OR=5.520, p<0.001) and barbiturate users (OR=17.109, p=0.01).

CONCLUSION

The study found that ATS use is widespread among Palestinian men and is associated with other drug use, including benzodiazepines, barbiturates and THC. The study recommends implementing better strategies and policies for controlling and confiscating illicit substances to address the severe medical and sociological problems that can arise from drug dependence. Additionally, the study highlights the risks associated with transitioning from marijuana to ATS, which can have severe clinical and social consequences.

摘要

引言

苯丙胺类兴奋剂(ATS)在约旦河西岸正日益引起关注。尽管人们主要关注大麻,但统计数据显示,ATS缉获量和秘密实验室表明,巴勒斯坦人中对这种极易成瘾的化学品的使用有所增加。从大麻转向ATS可能会产生严重的临床和社会后果,但相关研究却不足。我们的研究旨在评估约旦河西岸北部巴勒斯坦男性中ATS的使用 prevalence及其与其他药物使用的相关性。

方法

2022年至2023年,对约旦河西岸北部年龄≥18岁的巴勒斯坦男性进行了一项横断面研究。使用自填问卷和尿液分析测试来确定药物使用情况。本研究中的ATS使用者对以下至少一种药物检测呈阳性:苯丙胺、摇头丸或甲基苯丙胺。

结果

在787名参与者中,129人(16.4%)为吸毒者。吸毒者中各类药物的使用 prevalence如下:苯二氮卓类(55.8%)、苯丙胺(41.1%)、四氢大麻酚(THC)(38.8%)、甲基苯丙胺(38.0%)、巴比妥类(9.3%)、苯环利定(1.6%)和ATS(48.8%);84.1%为苯丙胺使用者,77.7%为甲基苯丙胺使用者。大多数ATS使用者(68.3%)为多药使用者;57.1%使用苯二氮卓类,30.2%使用THC,12.7%使用巴比妥类。经调整的二元逻辑回归显示,ATS使用者更有可能使用苯二氮卓类(OR=11.059,p<0.001)、THC(OR=5.520,p<0.001)和巴比妥类(OR=17.109,p=0.01)。

结论

研究发现,ATS在巴勒斯坦男性中广泛使用,并与其他药物使用有关,包括苯二氮卓类、巴比妥类和THC。该研究建议实施更好的控制和没收非法物质的战略和政策,以解决药物依赖可能引发的严重医学和社会学问题。此外,该研究强调了从大麻转向ATS的风险,这可能会产生严重的临床和社会后果。

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Benzodiazepine Use and Misuse Among Adults in the United States.美国成年人中苯二氮䓬类药物的使用和滥用情况。
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