Fu Hongjuan, Wang Congcong
Department of Anesthesiology, Yangguangronghe Hospital, Weifang, Shandong, China.
Department of Joint Surgery, Weifang People's Hospital, Weifang, Shandong, China.
Medicine (Baltimore). 2025 Feb 28;104(9):e41724. doi: 10.1097/MD.0000000000041724.
Subcutaneous adipose tissue provides distinct advantages as a source of mesenchymal stem cells due to its accessibility and the ease of isolating stem cells. Human adipose stem cells, located in the stromal-vascular fraction, can be harvested using mechanical methods to produce microfragmented adipose tissue (MFAT). Local injections of MFAT have shown potential in promoting natural tissue regeneration. This review introduces the concept of MFAT, highlights its clinical applications, and explores its potential in regenerative medicine, offering insights into its role as an innovative therapeutic approach.
皮下脂肪组织作为间充质干细胞的来源具有明显优势,这得益于其易于获取以及分离干细胞的便利性。位于基质血管部分的人类脂肪干细胞可以通过机械方法采集,以产生微片段化脂肪组织(MFAT)。局部注射MFAT已显示出促进天然组织再生的潜力。本综述介绍了MFAT的概念,突出其临床应用,并探讨其在再生医学中的潜力,为其作为一种创新治疗方法的作用提供见解。