Caroli G, Armani G, Levrè E, Valentini P
Quad Sclavo Diagn. 1979 Jun;15 Suppl 1:685-90.
Only ninety-three strains of Shigella, eightyseven of which have been identified as S. sonnei and six as S. flexneri were collected during 1969-1976 at the Pathogen Enterobacteria Centre of Pisa in Central Italy, as evidence of an epidemiological situation marked by a rare occurrence of syndromes related to these organisms. The collected strains were tested with disks of nine antibacterial drugs in common use: the survey detected sensitivity of all the strains to cephaloridine, ampicillin, carbenicillin, kanamycin and gentamicin, whereas a fair percentage of resistance appeared to streptomycin, tetracycline, chloramphenicol and cotrimoxazole. Both within multiresistant strains and those characterized by single resistances (forty-three of them in all), were present strains capable of transferring different drug resistance patterns to E. coli K-12, as evidence of being under extrachromosomial genetic control.
1969年至1976年间，在意大利中部比萨的病原菌肠道杆菌中心仅收集到93株志贺氏菌，其中87株已鉴定为宋内志贺氏菌，6株为福氏志贺氏菌，这证明了一种流行病学情况，即与这些生物体相关的综合征很少发生。用九种常用抗菌药物的药敏纸片对收集到的菌株进行了检测：调查发现所有菌株对头孢菌素、氨苄青霉素、羧苄青霉素、卡那霉素和庆大霉素敏感，而对链霉素、四环素、氯霉素和复方新诺明有相当比例的耐药性。在多重耐药菌株和具有单一耐药性的菌株（总共43株）中，都存在能够将不同耐药模式转移到大肠杆菌K-12的菌株，这证明它们受染色体外遗传控制。
