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用于人工智能辅助评估肺部B线的即时超声平台的性能

Performance of a point-of-care ultrasound platform for artificial intelligence-enabled assessment of pulmonary B-lines.

作者信息

Labaf Ashkan, Åhman-Persson Linda, Husu Leo Silvén, Smith J Gustav, Ingvarsson Annika, Evaldsson Anna Werther

机构信息

Department of Clinical Sciences Lund, Cardiology, Section for Heart Failure and Valvular Disease, Lund University, Skåne University Hospital, Klinikgatan 15, Lund, 221 85, Sweden.

Department of Internal and Emergency Medicine, Skåne University Hospital, Malmö, Sweden.

出版信息

Cardiovasc Ultrasound. 2025 Mar 3;23(1):3. doi: 10.1186/s12947-025-00338-2.

DOI:10.1186/s12947-025-00338-2
PMID:40025516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11874383/
Abstract

BACKGROUND

The incorporation of artificial intelligence (AI) into point-of-care ultrasound (POCUS) platforms has rapidly increased. The number of B-lines present on lung ultrasound (LUS) serve as a useful tool for the assessment of pulmonary congestion. Interpretation, however, requires experience and therefore AI automation has been pursued. This study aimed to test the agreement between the AI software embedded in a major vendor POCUS system and visual expert assessment.

METHODS

This single-center prospective study included 55 patients hospitalized for various respiratory symptoms, predominantly acutely decompensated heart failure. A 12-zone protocol was used. Two experts in LUS independently categorized B-lines into 0, 1-2, 3-4, and ≥ 5. The intraclass correlation coefficient (ICC) was used to determine agreement.

RESULTS

A total of 672 LUS zones were obtained, with 584 (87%) eligible for analysis. Compared with expert reviewers, the AI significantly overcounted number of B-lines per patient (23.5 vs. 2.8, p < 0.001). A greater proportion of zones with > 5 B-lines was found by the AI than by the reviewers (38% vs. 4%, p < 0.001). The ICC between the AI and reviewers was 0.28 for the total sum of B-lines and 0.37 for the zone-by-zone method. The interreviewer agreement was excellent, with ICCs of 0.92 and 0.91, respectively.

CONCLUSION

This study demonstrated excellent interrater reliability of B-line counts from experts but poor agreement with the AI software embedded in a major vendor system, primarily due to overcounting. Our findings indicate that further development is needed to increase the accuracy of AI tools in LUS.

摘要

背景

人工智能(AI)在床旁超声(POCUS)平台中的应用迅速增加。肺部超声(LUS)上的B线数量是评估肺充血的有用工具。然而,解读需要经验,因此人们一直在追求AI自动化。本研究旨在测试主要供应商POCUS系统中嵌入的AI软件与视觉专家评估之间的一致性。

方法

这项单中心前瞻性研究纳入了55例因各种呼吸道症状住院的患者,主要是急性失代偿性心力衰竭患者。采用12区方案。两名LUS专家将B线独立分类为0、1 - 2、3 - 4和≥5。组内相关系数(ICC)用于确定一致性。

结果

共获得672个LUS区域,其中584个(87%)符合分析条件。与专家评审员相比,AI显著高估了每位患者的B线数量(23.5对2.8,p < 0.001)。AI发现的B线>5条的区域比例高于评审员(38%对4%,p < 0.001)。AI与评审员之间B线总数的ICC为0.28,逐区方法的ICC为0.37。评审员之间的一致性非常好,ICC分别为0.92和0.91。

结论

本研究表明专家对B线计数的评分者间可靠性极佳,但与主要供应商系统中嵌入的AI软件一致性较差,主要原因是计数过多。我们的研究结果表明,需要进一步开发以提高LUS中AI工具的准确性。

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本文引用的文献

1
Enhancing Lung Ultrasound Diagnostics: A Clinical Study on an Artificial Intelligence Tool for the Detection and Quantification of A-Lines and B-Lines.增强肺部超声诊断:一项关于用于检测和量化A线与B线的人工智能工具的临床研究。
Diagnostics (Basel). 2024 Nov 12;14(22):2526. doi: 10.3390/diagnostics14222526.
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2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.《2021年欧洲心脏病学会急性和慢性心力衰竭诊断与治疗指南》2023年聚焦更新
Eur Heart J. 2023 Oct 1;44(37):3627-3639. doi: 10.1093/eurheartj/ehad195.
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Lung ultrasound in acute and chronic heart failure: a clinical consensus statement of the European Association of Cardiovascular Imaging (EACVI).
急性和慢性心力衰竭中的肺部超声:欧洲心血管影像学会(EACVI)临床共识声明
Eur Heart J Cardiovasc Imaging. 2023 Nov 23;24(12):1569-1582. doi: 10.1093/ehjci/jead169.
4
Two- Versus 8-Zone Lung Ultrasound in Heart Failure: Analysis of a Large Data Set Using a Deep Learning Algorithm.心力衰竭的两区域与八区域肺超声:使用深度学习算法的大型数据集分析。
J Ultrasound Med. 2023 Oct;42(10):2349-2356. doi: 10.1002/jum.16262. Epub 2023 May 31.
5
Comparison of pulmonary congestion severity using artificial intelligence-assisted scoring versus clinical experts: A secondary analysis of BLUSHED-AHF.人工智能辅助评分与临床专家评估肺淤血严重程度的比较:BLUSHED-AHF 的二次分析。
Eur J Heart Fail. 2023 Jul;25(7):1166-1169. doi: 10.1002/ejhf.2881. Epub 2023 Jun 20.
6
Automated versus manual B-lines counting, left ventricular outflow tract velocity time integral and inferior vena cava collapsibility index in COVID-19 patients.新冠病毒肺炎患者中B线计数的自动与手动方法、左心室流出道速度时间积分及下腔静脉塌陷指数的比较
Indian J Anaesth. 2022 May;66(5):368-374. doi: 10.4103/ija.ija_1008_21. Epub 2022 May 19.
7
B-line quantification: comparing learners novice to lung ultrasound assisted by machine artificial intelligence technology to expert review.B线定量分析:比较在人工智能技术辅助下进行肺部超声检查的新手学习者与专家评估。
Ultrasound J. 2021 Jun 30;13(1):33. doi: 10.1186/s13089-021-00234-6.
8
WFUMB position paper on reverberation artefacts in lung ultrasound: B-lines or comet-tails?WFUMB 肺部超声回声伪像立场文件:B 线还是彗尾征?
Med Ultrason. 2021 Feb 18;23(1):70-73. doi: 10.11152/mu-2944.
9
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J Ultrasound Med. 2021 Nov;40(11):2369-2376. doi: 10.1002/jum.15620. Epub 2021 Jan 11.
10
Lung ultrasound-guided treatment in ambulatory patients with heart failure: a randomized controlled clinical trial (LUS-HF study).肺部超声引导治疗心力衰竭门诊患者:一项随机对照临床试验(LUS-HF 研究)。
Eur J Heart Fail. 2019 Dec;21(12):1605-1613. doi: 10.1002/ejhf.1604. Epub 2019 Oct 31.