• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

糖尿病患者克雷伯菌属所致颈部坏死性感染:一例报告

Klebsiella-Induced Necrotizing Neck Infection in a Patient With Diabetes: A Case Report.

作者信息

Alosaimi Abdulrahman, Banjar Murad A, Felemban Walaa A, Abulnassr Khalid A, Sabbagh Yasser A

机构信息

Department of Otolaryngology-Head and Neck Surgery, Ohud Hospital, Madinah, SAU.

College of Medicine, Rayan Medical College, Madinah, SAU.

出版信息

Cureus. 2025 Jan 30;17(1):e78244. doi: 10.7759/cureus.78244. eCollection 2025 Jan.

DOI:10.7759/cureus.78244
PMID:40026992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11871957/
Abstract

Necrotizing infections of the head and neck are uncommon, aggressive, and potentially fatal if not treated promptly. These infections are particularly prevalent among immunocompromised individuals, such as people with diabetes, due to impaired immune response and delayed healing. We present a 45-year-old male with uncontrolled diabetes who had a five-day history of progressive left-sided neck swelling and pain. Imaging studies revealed an extensive necrotizing infection of the submandibular, parotid, and parapharyngeal carotid spaces. The condition was managed with intravenous antibiotics, ultrasound-guided aspiration, surgical drainage, extensive debridement, and skin grafting. The isolated microorganism was Klebsiella pneumoniae. After three weeks of management, the patient was discharged without impairment or recurrence. This case underscores the significance of early diagnosis, proper antibiotic use, timely surgery, and collaboration in managing neck space necrotizing infections to prevent complications in high-risk patients.

摘要

头颈部坏死性感染并不常见,具有侵袭性,若不及时治疗可能致命。由于免疫反应受损和愈合延迟,这些感染在免疫功能低下的个体中尤为普遍,如糖尿病患者。我们报告一名45岁男性,患有未控制的糖尿病,有左侧颈部进行性肿胀和疼痛5天的病史。影像学检查显示下颌下、腮腺和咽旁颈动脉间隙广泛坏死性感染。通过静脉注射抗生素、超声引导下抽吸、手术引流、广泛清创和皮肤移植进行治疗。分离出的微生物是肺炎克雷伯菌。经过三周的治疗,患者出院时无功能障碍或复发。该病例强调了早期诊断、合理使用抗生素、及时手术以及在管理颈部间隙坏死性感染以预防高危患者并发症方面进行协作的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/edebe191c427/cureus-0017-00000078244-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/3e7acd59205d/cureus-0017-00000078244-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/fc56278c13ac/cureus-0017-00000078244-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/379ba4afb0a2/cureus-0017-00000078244-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/8a0293d7eddf/cureus-0017-00000078244-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/6e523f13c4da/cureus-0017-00000078244-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/edebe191c427/cureus-0017-00000078244-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/3e7acd59205d/cureus-0017-00000078244-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/fc56278c13ac/cureus-0017-00000078244-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/379ba4afb0a2/cureus-0017-00000078244-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/8a0293d7eddf/cureus-0017-00000078244-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/6e523f13c4da/cureus-0017-00000078244-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ec/11871957/edebe191c427/cureus-0017-00000078244-i06.jpg

相似文献

1
Klebsiella-Induced Necrotizing Neck Infection in a Patient With Diabetes: A Case Report.糖尿病患者克雷伯菌属所致颈部坏死性感染:一例报告
Cureus. 2025 Jan 30;17(1):e78244. doi: 10.7759/cureus.78244. eCollection 2025 Jan.
2
A 52-Year-Old Diabetic Man with Poor Dental Hygiene, Right Dental Abscess, and Parapharyngeal Abscess with Gas Gangrene Due to Klebsiella pneumoniae Infection, Presenting with Septic Shock and Multiorgan Failure, Who Recovered After Surgical Neck Debridement.一位 52 岁的糖尿病男性,口腔卫生差,右侧牙龈脓肿,并发咽旁脓肿和气性坏疽,由肺炎克雷伯菌感染引起,出现感染性休克和多器官衰竭,经颈侧切开清创术后恢复。
Am J Case Rep. 2023 Jun 24;24:e940376. doi: 10.12659/AJCR.940376.
3
Cervical Necrotizing Fasciitis in an Uncontrolled Diabetic Male Patient: A Multimodal Management Approach.一名血糖控制不佳的男性糖尿病患者的颈部坏死性筋膜炎:一种多模式管理方法
Cureus. 2025 Mar 25;17(3):e81177. doi: 10.7759/cureus.81177. eCollection 2025 Mar.
4
Pediatric necrotizing soft tissue infection after elective surgery: A case report and literature review.小儿择期手术后坏死性软组织感染:病例报告及文献复习。
Int J Pediatr Otorhinolaryngol. 2020 Nov;138:110195. doi: 10.1016/j.ijporl.2020.110195. Epub 2020 Jul 10.
5
Cervical necrotizing fasciitis due to klebsiella.由克雷伯菌引起的颈部坏死性筋膜炎。
Med J Malaysia. 2005 Dec;60(5):657-9.
6
Craniocervical necrotizing fasciitis secondary to parotid gland abscess.腮腺脓肿继发颅颈坏死性筋膜炎
Acta Otolaryngol. 2003 Aug;123(6):737-40. doi: 10.1080/00016480310000430.
7
Critical Chest Wall Necrotizing Fasciitis Triggered by Herpes Zoster: A Case Report.带状疱疹引发的严重胸壁坏死性筋膜炎:病例报告。
Am J Case Rep. 2024 Sep 15;25:e944186. doi: 10.12659/AJCR.944186.
8
Klebsiella pneumoniae cervical necrotizing fasciitis originating as an abscess.肺炎克雷伯菌引起的宫颈坏死性筋膜炎脓肿。
Am J Otolaryngol. 2012 Nov-Dec;33(6):764-6. doi: 10.1016/j.amjoto.2012.05.009. Epub 2012 Jul 16.
9
Fungal necrotizing fasciitis of the head and neck in 3 patients with uncontrolled diabetes.3例糖尿病控制不佳患者发生头颈部真菌性坏死性筋膜炎。
Ear Nose Throat J. 2014 Mar;93(3):E18-21.
10
Necrotizing fasciitis of the jaw, neck and mediastinum caused by Klebsiella oxytoca and Streptococcus constellatus: a case report.产酸克雷伯菌和星座链球菌致颌颈部及纵隔坏死性筋膜炎 1 例报告
Ann Palliat Med. 2021 Jul;10(7):8431-8436. doi: 10.21037/apm-20-2427. Epub 2021 May 11.

本文引用的文献

1
Comprehensive evaluation of deep neck infections: A retrospective analysis of 111 cases.颈部深部感染的综合评估:111例回顾性分析
Laryngoscope Investig Otolaryngol. 2024 Oct 25;9(5):e70027. doi: 10.1002/lio2.70027. eCollection 2024 Oct.
2
Type 2 Diabetes and its Impact on the Immune System.2型糖尿病及其对免疫系统的影响。
Curr Diabetes Rev. 2020;16(5):442-449. doi: 10.2174/1573399815666191024085838.
3
Monomicrobial Klebsiella pneumoniae necrotizing fasciitis: an emerging life-threatening entity.单纯克雷伯菌坏死性筋膜炎:一种新出现的危及生命的实体。
Clin Microbiol Infect. 2019 Mar;25(3):316-323. doi: 10.1016/j.cmi.2018.05.008. Epub 2018 May 19.
4
Necrotizing Soft-Tissue Infections.坏死性软组织感染
N Engl J Med. 2017 Dec 7;377(23):2253-2265. doi: 10.1056/NEJMra1600673.
5
Evaluation and Management of Necrotizing Soft Tissue Infections.坏死性软组织感染的评估与管理
Infect Dis Clin North Am. 2017 Sep;31(3):497-511. doi: 10.1016/j.idc.2017.05.011.
6
Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality.糖尿病患者的坏死性筋膜炎:临床特征及死亡风险因素
BMC Infect Dis. 2015 Oct 13;15:417. doi: 10.1186/s12879-015-1144-0.
7
Necrotizing fasciitis caused by hypermucoviscous Klebsiella pneumoniae in a Filipino female in North America.北美一名菲律宾女性因高黏液性肺炎克雷伯菌引起的坏死性筋膜炎。
West J Emerg Med. 2015 Jan;16(1):165-8. doi: 10.5811/westjem.2014.11.23599. Epub 2014 Dec 5.
8
Necrotizing fasciitis: eight-year experience and literature review.坏死性筋膜炎:八年经验和文献回顾。
Braz J Infect Dis. 2014 Mar-Apr;18(2):137-43. doi: 10.1016/j.bjid.2013.08.003. Epub 2013 Nov 22.
9
Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed.高毒力(高黏液性)肺炎克雷伯菌:一种新型且危险的病原体。
Virulence. 2013 Feb 15;4(2):107-18. doi: 10.4161/viru.22718. Epub 2013 Jan 9.
10
Infections in patients with diabetes mellitus: A review of pathogenesis.糖尿病患者的感染:发病机制综述
Indian J Endocrinol Metab. 2012 Mar;16 Suppl 1(Suppl1):S27-36. doi: 10.4103/2230-8210.94253.