Eskandarizadeh Ali, Parizi Molook Torabi, Goroohi Hossein, Badrian Hamid, Asadi Abbas, Khalighinejad Navid
Department of Restorative Dentistry and Oral and Dental Disease Research Center, Kerman, Iran.
Department of Oral and Maxillofacial Pathology and Oral and Dental Disease Research Center, Kerman, Iran.
Dent Res J (Isfahan). 2015 Mar-Apr;12(2):144-9.
The biocompatibility of resin-modified glass ionomers (RMGIs) as a lining material is still under question. The present study evaluated the response of the pulp-dentin complex following application of resin-modified glass-ionomer cement, calcium hydroxide and conventional glass-ionomer in deep cavities prepared in human teeth.
In this controlled clinical trial, 30 deep class V buccal cavities (3 mm × 2 mm × 2 mm) were prepared in human premolars treatment planned to be extracted for orthodontic reasons and divided into 3 groups. Groups were lined by a RMGI (Vivaglass), conventional glass Ionomer (Ionocid) and calcium hydroxide respectively. The cavities were subsequently filled with amalgam. Each group was then divided into two sub-groups according to time intervals 5 and 30 days. The patients were referred to Kerman Dental School and in accordance with orthodontic treatment plan; premolars were extracted and then prepared for histological assessment. The sections were stained with hematoxylin and eosin and periodic acid Schiff techniques. All of the samples were examined using a number of criteria including odontoblastic changes, inflammatory cells response, reactionary dentin formation and presence of microorganisms. The data were analyzed by Kruskal-Wallis and Mann-Whitney tests. P < 0.05 was considered as significant.
There was no significant difference among odontoblastic changes, reactionary dentin, presence of bacteria and inflammatory cells response of the groups (P > 0.05).
Ionocid and Vivaglass resin-modified glass ionomers can be used as lining materials in human teeth.
树脂改性玻璃离子水门汀（RMGIs）作为一种衬层材料的生物相容性仍存在疑问。本研究评估了在人类牙齿制备的深龋洞中应用树脂改性玻璃离子水门汀、氢氧化钙和传统玻璃离子水门汀后牙髓-牙本质复合体的反应。
在这项对照临床试验中，在计划因正畸原因拔除的人类前磨牙上制备30个深度为V类的颊侧洞（3mm×2mm×2mm），并分为3组。分别用RMGI（Vivaglass）、传统玻璃离子水门汀（Ionocid）和氢氧化钙进行衬层处理。随后用银汞合金填充龋洞。然后根据5天和30天的时间间隔将每组再分为两个亚组。患者被转诊至克尔曼牙科学院，并按照正畸治疗计划；拔除前磨牙，然后制备用于组织学评估的样本。切片用苏木精和伊红以及过碘酸希夫技术染色。所有样本均根据包括成牙本质细胞变化、炎症细胞反应、反应性牙本质形成和微生物存在等多项标准进行检查。数据采用Kruskal-Wallis和Mann-Whitney检验进行分析。P<0.05被认为具有统计学意义。
各组在成牙本质细胞变化、反应性牙本质、细菌存在和炎症细胞反应方面无显著差异（P>0.05）。
Ionocid和Vivaglass树脂改性玻璃离子水门汀可作为人类牙齿的衬层材料。
