[Relation of uteroplacental circulation and morphologic findings in myometrial and decidual arteries in diabetic pregnancy].

Placental blood flow measurements are compared to morphologic blood vessel examinations of the placental bed and uterus. In 122 diabetic pregnant women half life time of 113m Indium labelled blood inflow curves into the placenta as measured by a gamma scintillation camera on-line recorded to a computer system. - In 57 patients histological examination of uteroplacental arteries were done. - Congruent results of placental blood flow and arterial morphology were found in 66%. - In almost all patients with normal placental blood flow extensive physiological vessel findings were recorded. In patients with reduced placental blood flow pathomorphological changes were found in 54%. - In diabetes of long duration with angiopathic complications - above all in White-classes D, F and R - the ratio of pathological findings in placental blood flow and morphology was increased. - But also in gestational diabetes and in disturbances of carbohydrate metabolism pathological results are to be found. Pathological results in placental blood flow were more often than morphological changes (70 versus 40%), so that also functional factors as uteroplacental blood flow influencing ones are to be taken into account.