[Blood supply of the organs in the pregnant and non-pregnant guinea pig with special reference to uteroplacental blood flow (author's transl)].

The relative and specific maternal blood flow to the placenta and other organs at 15 pregnant and 16 non pregnant guinea pigs (Pirbright White) was determined by using the microspheres-method (Tc 99m). Renal blood flow of the pregnant guinea pigs decreases for about 30% in comparison to the non pregnant animals (2 p less than 0.005). The uterine blood flow to the left and right horn does not differ significantly. mean = 6.9% from the cardiac output are directed to uterus, placenta and ovary. Refer to the uterus and its content the specific blood flow is 5.9 (SD = 2.5) ml . min-1 . 100 g-1. The specific uteroplacental blood flow depends on the cardiac output (2 p less than 0.05). 75% of the uteroplacental blood flow are directed to the placenta and 25% to the myometrium. This relation is not constant and depends on the mean maternal arterial blood pressure (2 p less than 0.005).