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用于评估抗晕动病设备的晕船模拟器

Seasickness Simulator to Assess Anti-Motion Sickness Devices.

作者信息

de Thierry de Faletans Camille, Misericordia Maxime, Vallier Jean-Marc, Duché Pascale, Watelain Eric

出版信息

Aerosp Med Hum Perform. 2025 Mar;96(3):212-218. doi: 10.3357/AMHP.6403.2025.

DOI:10.3357/AMHP.6403.2025
PMID:40029344
Abstract

INTRODUCTION

There are various motion sickness (MS) simulators in the laboratory, but the conditions under which they induce MS symptoms are different from real-life conditions. This study aimed to design a seasickness simulator, close to ecological conditions, easy to set up, at a modest cost, and capable of rapidly inducing MS symptoms, to evaluate the effect of anti-motion sickness devices. The hypothesis was that this simulator would induce MS, reflecting the susceptibility of subjects in real-life conditions, meaning the more susceptible individuals were to MS in real conditions, the more severe and rapid their symptoms would be in the simulator.

METHODS

A total of 65 subjects with varying degrees of MS susceptibility (MS Susceptibility Questionnaire Short form) were exposed to a seasickness simulator for a maximum of 10 min. Measurements of subjective symptoms (Visual Analog Scale and time to onset of first symptoms) and physiological variables (heart rate and temperature) were taken.

RESULTS

Subjects covered the full range of MS susceptibility (from 0-100%). The average time in the simulator before the first symptoms of MS was 7.41 min ± 2.56 min. The time to onset of the first symptoms, the intensity of the symptoms, and heart rate were significantly correlated with the degree of susceptibility of subjects in real-life conditions.

DISCUSSION

The simulator induced varying intensity of MS depending on the subjects' susceptibility. It thus replicates real-life conditions and can serve as a useful tool for facilitating the research of devices, techniques, and medications to combat MS. de Thierry de Faletans C, Misericordia M, Vallier J-M, Duché P, Watelain E. Seasickness simulator to assess anti-motion sickness devices. Aerosp Med Hum Perform. 2025; 96(3):212-218.

摘要

引言

实验室中有各种晕动病(MS)模拟器,但它们诱发MS症状的条件与现实生活中的条件不同。本研究旨在设计一种接近生态条件、易于设置、成本适中且能够快速诱发MS症状的晕船模拟器,以评估抗晕动病设备的效果。假设是该模拟器将诱发MS,反映受试者在现实生活条件下的易感性,即个体在现实条件下对MS越易感,其在模拟器中的症状就会越严重且出现得越快。

方法

共有65名具有不同程度MS易感性(MS易感性简短问卷)的受试者暴露于晕船模拟器中,最长时间为10分钟。测量主观症状(视觉模拟量表和首次症状出现时间)和生理变量(心率和体温)。

结果

受试者涵盖了MS易感性的全范围(从0 - 100%)。MS首次症状出现前在模拟器中的平均时间为7.41分钟±2.56分钟。首次症状出现时间、症状强度和心率与受试者在现实生活条件下的易感性程度显著相关。

讨论

模拟器根据受试者的易感性诱发不同强度的MS。因此,它复制了现实生活条件,可作为促进抗MS设备、技术和药物研究的有用工具。德·蒂埃里·德·法莱坦斯C、米塞里科迪亚M、瓦利耶J - M、迪谢P、瓦泰兰E。用于评估抗晕动病设备的晕船模拟器。航空航天医学与人类表现。2025年;96(3):212 - 218。

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