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Gases define redox signalling: NO, HS, O … and cyanide.

作者信息

Grimmett Zachary W, Schindler Joseph C, Stamler Jonathan S

机构信息

Medical Scientist Training Program, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Institute for Transformative Molecular Medicine, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

出版信息

Nat Metab. 2025 Mar;7(3):444-446. doi: 10.1038/s42255-025-01229-6.

DOI:10.1038/s42255-025-01229-6
PMID:40033005
Abstract
摘要

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An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling.一种通过选择性地对蛋白质进行S-亚硝基化来调节胰岛素信号传导的酶。
Cell. 2023 Dec 21;186(26):5812-5825.e21. doi: 10.1016/j.cell.2023.11.009. Epub 2023 Dec 5.
3
Old poisons, new signaling molecules: the case of hydrogen cyanide.旧毒物，新信号分子：氰化氢案例。
J Exp Bot. 2023 Oct 13;74(19):6040-6051. doi: 10.1093/jxb/erad317.
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A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.多酶 S-亚硝基化级联反应调节胆固醇稳态。
Cell Rep. 2022 Oct 25;41(4):111538. doi: 10.1016/j.celrep.2022.111538.
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Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.S-亚硝基辅酶 A 还原酶系统通过代谢重编程来保护肾脏免受损伤。
Nature. 2019 Jan;565(7737):96-100. doi: 10.1038/s41586-018-0749-z. Epub 2018 Nov 28.
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HCN Regulates Cellular Processes through Posttranslational Modification of Proteins by cyanylation.氰基化通过翻译后修饰蛋白质来调节细胞过程。
Plant Physiol. 2019 Jan;179(1):107-123. doi: 10.1104/pp.18.01083. Epub 2018 Oct 30.
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A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation.一种用于细胞蛋白质 S-亚硝基化的多重酶促机制。
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The Role of Hydrogen Sulfide in Evolution and the Evolution of Hydrogen Sulfide in Metabolism and Signaling.硫化氢在进化中的作用以及硫化氢在代谢和信号传导中的演变
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