Li Fei, Ma Yueni, Qi Wenjie, Pazo Emmanuel Eric, Yang Ruibo, Zhao Shaozhen
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute, School of Optometry, Tianjin Medical University Eye Hospital, No. 251, Fukang Road, Nankai District, Tianjin, 30384, China.
BMC Ophthalmol. 2025 Mar 3;25(1):103. doi: 10.1186/s12886-025-03934-y.
To analyze the characteristics of anterior segment biometric parameters in moderate, high, and super-high myopia eyes for ICL size selection.
A total of 246 eyes of 131 patients were included in this prospective observational cohort study. Preoperative axis length (AL), central keratometry (Kc), central corneal thickness (CCT), white-to-white (WTW), internal anterior chamber depth (ACD), trabecular iris angle (TIA), anterior chamber width (ACW), angle-to-angle distance (ATA), crystalline lens rise (CLR), lens thickness (LT), sulcus-to-sulcus (STS), ICL size, and postoperative vault at 1 month were recorded and compared among the different degrees of myopia groups.
The moderate myopia showed smaller ACD and TIA than high and super-high myopia (P < 0.05). A higher proportion of CLR positive (+) was in the moderate myopia group (65%), while the super-high myopia group had a higher proportion of CLR negative (-) (55.3%). (P = 0.047). There were no statistical differences among the myopia groups in WTW, ATA, ACW, STS, LT, and postoperative vault (P>0.05). In different degrees of myopia groups, vertical ATA, ACW and STS were longer than horizontal ATA, ACW and STS (P < 0.001), and horizontal-STS showed a higher correlation with horizontal-ATA (r = 0.655) and horizontal-ACW (r = 0.660) than with WTW (r = 0.591). The 12.1 mm size ICL was slightly selected in moderate myopia (35.8%) more than high myopia (14.6%) and super-high myopia (26.3%) (P = 0.013).
Compared to high and super-high myopia, moderate myopic eyes exhibited smaller ACD, TIA while similar WTW, ATA, ACW and STS, with the lens positioned more anteriorly. It should be concerned to the effect of sagittal axis parameters ACD and CLR on the ICL size in different degrees of myopia.
分析中度、高度和超高度近视眼中眼前节生物测量参数的特征,以选择合适的ICL尺寸。
本前瞻性观察队列研究共纳入131例患者的246只眼。记录术前眼轴长度(AL)、中央角膜曲率(Kc)、中央角膜厚度(CCT)、白对白(WTW)、前房深度(ACD)、小梁虹膜角(TIA)、前房宽度(ACW)、角对角距离(ATA)、晶状体抬高(CLR)、晶状体厚度(LT)、沟到沟(STS)、ICL尺寸以及术后1个月的拱高,并在不同近视程度组之间进行比较。
中度近视的ACD和TIA小于高度和超高度近视(P<0.05)。中度近视组CLR阳性(+)的比例较高(65%),而超高度近视组CLR阴性(-)的比例较高(55.3%)(P=0.047)。各近视组在WTW、ATA、ACW、STS、LT和术后拱高方面无统计学差异(P>0.05)。在不同近视程度组中,垂直ATA、ACW和STS长于水平ATA、ACW和STS(P<0.001),水平STS与水平ATA(r=0.655)和水平ACW(r=0.660)的相关性高于与WTW(r=0.591)的相关性。中度近视(35.8%)选择12.1mm尺寸ICL的比例略高于高度近视(14.6%)和超高度近视(26.3%)(P=0.013)。
与高度和超高度近视相比,中度近视眼中ACD、TIA较小,而WTW、ATA、ACW和STS相似,晶状体位置更靠前。不同近视程度下矢状轴参数ACD和CLR对ICL尺寸的影响应予以关注。