Relentless Headaches and Syncope: A Case of Neuropsychiatric Systemic Lupus Erythematosus in a Pediatric Male Patient.

Childhood systemic lupus erythematosus (cSLE) is a rare multisystem autoimmune disease with considerable morbidity as it has been typically reported to be more severe than in adults. Neuropsychiatric SLE (NPSLE) is the second leading cause of lupus-related morbidity in the pediatric age group, mostly occurring within the first year of onset, but may develop at any time. It can present with a range of vague specific neurologic manifestations which can be challenging to diagnose. Here, we present a case of NPSLE in an 11-year-old male, presenting less than a month after diagnosis with positive radiologic features.