影响范围：寄生虫细胞生物学不断扩展的领域。
mSphere of Influence: The ever-expanding universe of parasite cell biology.
作者信息
Liffner Benjamin
机构信息
School of Biological Sciences, Faculty of Science, Engineering, & Technology, University of Adelaide, Adelaide, South Australia, Australia.
Institute for Photonics and Advanced Sensing (IPAS), University of Adelaide, Adelaide, South Australia, Australia.
出版信息
mSphere. 2025 Mar 25;10(3):e0004325. doi: 10.1128/msphere.00043-25. Epub 2025 Mar 4.
Ben Liffner studies the cell biology of apicomplexan parasites. In this mSphere of Influence article, he reflects on two key papers: "Three-dimensional ultrastructure of throughout cytokinesis" by R. M. Rudlaff, S. Kraemer, J. Marshman, J. D. Dvorin, et al. (PLoS Pathog 16:e1008587, 2020, https://doi.org/10.1371/journal.ppat.1008587) and "Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid" by E. Bertiaux, A. C. Balestra, L. Bournonville, V. Louvel, et al. (PLoS Biol 19:e3001020, 2021, https://doi.org/10.1371/journal.pbio.3001020). These two studies provided Ben with the conceptual framework to understand how parasites are organized in three dimensions, and the technique of ultrastructure expansion microscopy that he has since used to investigate this intriguing area of biology.
本·利夫纳研究顶复门寄生虫的细胞生物学。在这篇《mSphere of Influence》文章中，他对两篇关键论文进行了反思：R.M. 鲁德洛夫、S. 克雷默、J. 马什曼、J.D. 德沃林等人发表的《整个胞质分裂过程中的三维超微结构》（《公共科学图书馆·病原体》16：e1008587，2020年，https://doi.org/10.1371/journal.ppat.1008587），以及E. 贝蒂奥、A.C. 巴莱斯特拉、L. 布尔农维尔、V. 卢韦尔等人发表的《扩展显微镜技术为疟原虫细胞骨架提供了新见解，包括类锥体的保守性》（《公共科学图书馆·生物学》19：e3001020，2021年，https://doi.org/10.1371/journal.pbio.3001020）。这两项研究为本提供了一个概念框架，以理解寄生虫在三维空间中的组织方式，以及超微结构扩展显微镜技术，自那以后他一直用该技术来研究这个有趣的生物学领域。
Zotero 插件