Beardslee W R, Klerman G L, Keller M B, Lavori P W, Podorefsky D L
Am J Psychiatry. 1985 Jun;142(6):687-91. doi: 10.1176/ajp.142.6.687.
The authors examine the validity of the diagnosis of major depression in nine children and adolescents assessed as part of a study of offspring of parents who had affective disorders. The authors conclude that these nine children were suffering from valid cases of affective disorder because disruptions in multiple domains of functioning accompanied the major depression. The seriousness of the impairment and the finding that few of these children received any treatment at all strongly suggest the need for a heightened awareness among clinicians about the seriousness of depression in children whose parents have affective disorders.
作者们对九名儿童和青少年的重度抑郁症诊断有效性进行了检查，这些儿童和青少年是作为一项针对患有情感障碍的父母的后代的研究的一部分进行评估的。作者们得出结论，这九名儿童患有有效的情感障碍病例，因为重度抑郁症伴随着多个功能领域的紊乱。功能损害的严重性以及这些儿童中几乎无人接受任何治疗这一发现，强烈表明临床医生需要提高对父母患有情感障碍的儿童抑郁症严重性的认识。
