Miller A L, Faber R A, Hatch J P, Alexander H E
Am J Psychiatry. 1985 Jun;142(6):692-6. doi: 10.1176/ajp.142.6.692.
Twenty-nine patients given unilateral ECT were tested for memory with each treatment. Forgetting of nonverbal material correlated positively with seizure duration and with anesthetic dose. Seizure duration did not correlate with forgetting of verbal material or with changes in Hamilton depression ratings. Seizure duration was inversely related to succinylcholine and methohexital doses. These findings suggest that muscle relaxant and anesthetic doses can be adjusted to lessen the amnestic effects of ECT. There are, however, insufficient data on the relationship between seizure length and ECT efficacy to specify a minimum duration for seizures, individually or cumulatively.
对29例接受单侧电休克治疗（ECT）的患者在每次治疗时进行记忆测试。非言语材料的遗忘与癫痫发作持续时间和麻醉剂量呈正相关。癫痫发作持续时间与言语材料的遗忘或汉密尔顿抑郁评分的变化无关。癫痫发作持续时间与琥珀酰胆碱和甲己炔巴比妥剂量呈负相关。这些发现表明，可以调整肌肉松弛剂和麻醉剂的剂量以减轻ECT的遗忘效应。然而，关于癫痫发作时长与ECT疗效之间的关系，尚无足够数据来确定癫痫发作的最短时长，无论是单次还是累计时长。
