Khallaf Mohamed, Jaber Hatem, Alameri Mansoor, Magdy Dina, Kamal Hend, Hassanin Mohamed, Mousa Mohamed, Fayed Eman
Department of Physical Therapy, University of St. Augustine for Health Sciences, Austin, Texas, USA.
Department of Physical Therapy for Neuromuscular Disorders and Its Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Neurol Res Int. 2025 Feb 25;2025:6846267. doi: 10.1155/nri/6846267. eCollection 2025.
Parkinson's disease is a neurodegenerative disorder that affects balance and increases the risk of falling by compromising vestibular signal processing. This study aims to assess the impact of vestibular-oriented balance training on postural control and fall risk among people in the middle stages of PD. Forty middle-stage individuals with PD were assigned to the vestibular-oriented balance training (study group) or the traditional balance training (control group). Outcome measures including Functional Gait Assessment (FGA) and modified Clinical Test of Sensory Interaction on Balance (mCTSIB) using the Biodex Balance System were measured before, immediately after and 4 weeks after treatment. There was a significant group interaction by time for all outcome measures ( < 0.001). The results showed that the difference in the FGA and mCTSIB scores from baseline was significant between the two groups at all time points ( < 0.001). The study group showed significant sustained improvements in the FGA score overtime, while the control group had a significant improvement at Week 8 but that did not last to Week 12. In mCTSIB, the study group improved significantly in all test conditions ( < 0.001), while the control group showed significant improvement only in Conditions 1 and 2, without lasting effects at Week 12 ( > 0.05). The findings indicate that the implementation of vestibular-oriented balance training during the middle stage of PD might have a notable and lasting impact on both postural control and the risk of falls.
帕金森病是一种神经退行性疾病，会影响平衡，并通过损害前庭信号处理增加跌倒风险。本研究旨在评估以前庭为导向的平衡训练对帕金森病中期患者姿势控制和跌倒风险的影响。40名帕金森病中期患者被分配到以前庭为导向的平衡训练组（研究组）或传统平衡训练组（对照组）。使用Biodex平衡系统，在治疗前、治疗后立即以及治疗后4周测量包括功能性步态评估（FGA）和改良的平衡感觉交互临床测试（mCTSIB）在内的结果指标。所有结果指标在时间上均存在显著的组间交互作用（<0.001）。结果显示，在所有时间点，两组FGA和mCTSIB评分与基线的差异均具有显著性（<0.001）。研究组FGA评分随时间持续显著改善，而对照组在第8周有显著改善，但在第12周未持续。在mCTSIB中，研究组在所有测试条件下均有显著改善（<0.001），而对照组仅在条件1和条件2中有显著改善，在第12周无持续效果（>0.05）。研究结果表明，在帕金森病中期实施以前庭为导向的平衡训练可能对姿势控制和跌倒风险产生显著且持久的影响。
