Sanchez Goddard Gala Paulina, Rodriguez Partida Perla Selene, Aguilar Salas Ismael, Guzmán González Héctor Eduardo
Department of Education, Ramón de la Fuente Muñiz National Institute of Psychiatry, Mexico City, MEX.
Department of Hospitalization, Ramón de la Fuente Muñiz National Institute of Psychiatry, Mexico City, MEX.
Cureus. 2025 Mar 4;17(3):e80035. doi: 10.7759/cureus.80035. eCollection 2025 Mar.
Antisocial personality disorder (APD) is mainly based on social irresponsibility that leads to delinquent, criminal, and exploitative behavior toward others, as well as difficulty in adapting to social norms. This disorder predominates in the male gender, and therefore, most of the research to date has been conducted in men. In the following study, we aimed to describe the main sociodemographic variables and psychiatric comorbidities presented in women with a diagnosis of APD.
We assessed 54 women with a diagnosis of APD, of whom sociodemographic characteristics were collected, and the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders-IV Axis II Disorders (SCID-II) and the Mini-International Neuropsychiatric Interview (M.I.N.I.) 5.0.0 were applied.
We found a weak positive correlation with the obsessive ( = 0.28, = 0.039), passive-aggressive ( = 0.29, = 0.034), paranoid ( = 0.39, = 0.004), narcissistic ( = 0.36, = 0.008), and borderline ( = 0.35, = 0.010) personality domains, with a median age of 24.00 (IQR = 11.50) years, and the majority mainly being single and unemployed. We also found high rates of suicidal risk, depression, anxiety, and substance abuse, which was consistent with what has been reported elsewhere.
Research on APD and its comorbidities in women is limited, especially in Mexico, where women with APD show similar patterns to those in developed countries. This suggests the need for gender-specific interventions and a dimensional approach to improve the diagnosis and treatment of APD.
反社会人格障碍（APD）主要表现为对他人有导致犯罪、违法及剥削行为的社会不负责任，以及难以适应社会规范。这种障碍在男性中更为普遍，因此，迄今为止的大多数研究都是在男性中进行的。在以下研究中，我们旨在描述被诊断为APD的女性所呈现的主要社会人口统计学变量和精神共病情况。
我们评估了54名被诊断为APD的女性，收集了她们的社会人口统计学特征，并应用了《精神障碍诊断与统计手册》第四版轴II障碍的结构化临床访谈（SCID-II）和迷你国际神经精神病学访谈（M.I.N.I.）5.0.0。
我们发现与强迫型（= 0.28，= 0.039）、被动攻击型（= 0.29，= 0.034）、偏执型（= 0.39，= 0.004）、自恋型（= 0.36，= 0.008）和边缘型（= 0.35，= 0.010）人格领域存在微弱正相关，中位年龄为24.00（四分位间距 = 11.50）岁，大多数人主要为单身且失业。我们还发现自杀风险、抑郁、焦虑和物质滥用的发生率很高，这与其他地方报道的情况一致。
关于女性APD及其共病的研究有限，尤其是在墨西哥，患有APD的女性表现出与发达国家相似的模式。这表明需要针对性别的干预措施和维度方法来改善APD的诊断和治疗。
