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探索猝死和意外死亡中的非创伤性脑出血:一项基于尸检的新型调查。

Exploring Nontraumatic Brain Hemorrhage in Sudden and Unexpected Deaths: A Novel Autopsy-Based Investigation.

作者信息

Kanani Jayeshkumar, Sheikh Mohammed Iliyas

机构信息

Department of Forensic Medicine and Toxicology, Surat Municipal Institute of Medical Education and Research, Umarvada, Surat, Gujarat, India.

出版信息

Asian J Neurosurg. 2024 Dec 2;20(1):126-131. doi: 10.1055/s-0044-1800811. eCollection 2025 Mar.

Abstract

There has been a surge in sudden and unexpected deaths, presenting a significant challenge for health policymakers and researchers. These individuals showed no signs of recent or past illnesses and died suddenly during routine activities like walking, standing, or working.  This study focuses on exploring nontraumatic brain hemorrhage as a cause of death in autopsies of individuals without prior illnesses. The research aims to explore patterns, prevalence, and risk factors associated with nontraumatic brain hemorrhage, specifically obesity in sudden and unexpected deaths.  This retrospective, observational study was conducted using autopsy cases with nontraumatic brain hemorrhage as the identified cause of sudden and unexpected deaths. Information on demographic details, medical history, and circumstances surrounding the deaths was collected. The cases were classified based on the body mass index according to the classification of the World Health Organization.  From April 2023 to January 2024, 10 cases of sudden and unexpected deaths due to nontraumatic brain hemorrhage were identified. Key findings included predominantly cases of obesity or overweight, deaths occurring predominantly between 8 p.m. and midnight, and all cases being males.  The study sheds light on the surge in sudden deaths, specifically attributed to nontraumatic brain hemorrhage. The findings reveal a significant association between obesity and brain hemorrhage in sudden deaths, especially among males. The study's temporal analysis adds depth to understanding these patterns.

摘要

突发意外死亡事件激增,给卫生政策制定者和研究人员带来了重大挑战。这些人近期或过去均无疾病迹象,却在行走、站立或工作等日常活动中突然死亡。

本研究聚焦于在无既往疾病个体的尸检中探索非创伤性脑出血作为死因的情况。该研究旨在探究与非创伤性脑出血相关的模式、患病率及风险因素,特别是在突发意外死亡中的肥胖因素。

这项回顾性观察研究使用了以非创伤性脑出血作为突发意外死亡明确死因的尸检病例。收集了人口统计学细节、病史以及死亡相关情况的信息。根据世界卫生组织的分类标准,依据体重指数对病例进行分类。

2023年4月至2024年1月期间,共确定了10例因非创伤性脑出血导致的突发意外死亡病例。主要发现包括肥胖或超重病例占主导、死亡主要发生在晚上8点至午夜之间,且所有病例均为男性。

该研究揭示了突发死亡事件的激增情况,特别是归因于非创伤性脑出血的情况。研究结果显示,肥胖与突发死亡中的脑出血之间存在显著关联,尤其是在男性中。该研究的时间分析为理解这些模式增添了深度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f2d/11875705/69db0686a02d/10-1055-s-0044-1800811-i2440006-1.jpg

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