Angeloni D, Gamba S, Zanno C, Gandolfo Caramello M T, Bruni B
Ann Osp Maria Vittoria Torino. 1979 Jan-Jun;22(1-6):56-71.
Blood lactate levels were determined by Lactate Analyzer 640 Kontron in 5 infants of diabetic mothers with pregestational insulin-dependent-diabetes, class B-C-D White, BPSP negative, in strict glycemic control all along the pregnancy. In the mothers blood lactate was found in a normal range after-delivery. In the absence of complications, the neonate of diabetic mother did not show blood lactate changes above the normal range. As well as in the neonate of non diabetic mother, blood lactate increases were found only in concomitance with respiratory acidosis. In the cases with favourable course, lactate values above 2 mmol/l were normalized in the first 24 hours after the birth. The semiautomatic determination of blood lactate supplies a good prognostic evaluation of the association between metabolic and respiratory acidosis in the neonate and should therefore be routinely used in centers for management of diabetic pregnancy.
采用康强640乳酸分析仪对5例患有孕前胰岛素依赖型糖尿病、White分级为B - C - D级、BPSP阴性且孕期血糖一直严格控制的糖尿病母亲所生婴儿测定血乳酸水平。母亲产后血乳酸在正常范围内。在无并发症的情况下，糖尿病母亲的新生儿血乳酸未出现高于正常范围的变化。与非糖尿病母亲的新生儿一样，血乳酸升高仅在合并呼吸性酸中毒时出现。在病情转好的病例中，出生后24小时内血乳酸值高于2 mmol/L的情况恢复正常。血乳酸的半自动测定可为新生儿代谢性酸中毒和呼吸性酸中毒之间的关联提供良好的预后评估，因此应在糖尿病妊娠管理中心常规使用。
