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经皮肾镜取石术治疗肾结石:疗效与并发症的审计

Percutaneous Nephrolithotomy in the Management of Renal Stone: An Audit of Outcomes and Complications.

作者信息

Akpayak Idorenyin Cletus, Ikeh Chukwudum Dennis

机构信息

Department of Surgery, Division of Urology, Jos University Teaching Hospital, Jos, Nigeria.

出版信息

Ann Afr Med. 2025 Apr 1;24(2):461-467. doi: 10.4103/aam.aam_5_25. Epub 2025 Mar 7.

Abstract

BACKGROUND

Percutaneous nephrolithotomy (PCNL) is considered one of the most significant advances in minimally invasive urologic surgery. It offers a better stone-free rate compared to other available treatment modalities of renal stones at a lower complication rate compared to open surgery. Despite the availability of extracorporeal shock wave lithotripsy and flexible ureteroscopy, PCNL remains the gold standard modality for large and complex renal stones. Here, we review our initial experience with standard PCNL in the prone position for renal stones >1.5 cm with respect to stone clearance rate and complications as seen in our patients.

PATIENTS AND METHODS

Records of 24 patients who had standard PCNL and pneumatic lithotripsy between September 2020 and September 2023 were reviewed retrospectively. All the patients who had the standard PCNL for renal stones >1.5 cm were the subjects of this study. Data on patients' demographics, indication for the surgery, location of stone, size of stone, postoperative nephrostomy placement, nephrostomy tract size, complications, duration of surgery, duration of hospital stay, and status of stone clearance were obtained, and the data were subjected to statistical analysis.

RESULTS

A total of 24 patients underwent the standard PCNL. The mean age of the patients was 47.0 ± 10.28 years (16 males and 8 females; range: 17-68 years). Flank pain was the main indication for the surgery. The mean stone size was 2.5 cm (range: 1.6-3.3 cm). The mean Hounsfield unit was 1248.2 HU (range: 927-1502HU). At a single session, we achieved 100% stone clearance in 20 (83.3%) patients. Two (8.3%) of our patients required a second session of PCNL due to intraoperative bleeding and perforation of the pelvicalyceal system necessitating termination of the procedure and insertion of nephrostomy tube. In another 2 (8.3%) patients, the stones migrated and became inaccessible. One (4.2%) patient stayed for 10 days due to persistent urine leak, which eventually stopped after the insertion of a double-J stent and administration of antibiotics. The Clavien-Dindo grading system was used to classify postoperative complications. A total of 14 (58.3%) patients had Grade I complications, while 3 (12.5%) patients had Grade II and 1 (4.2%) had Grade IIIa complications.

CONCLUSION

PCNL is an effective minimally invasive technique for the treatment of large renal stones. Our initial experience suggests that the complication rate in PCNL is well within the acceptable limit.

摘要

背景

经皮肾镜取石术(PCNL)被认为是微创泌尿外科手术中最重要的进展之一。与其他现有的肾结石治疗方式相比,它具有更高的结石清除率,且与开放手术相比并发症发生率更低。尽管有体外冲击波碎石术和软性输尿管镜检查,但PCNL仍然是治疗大的复杂性肾结石的金标准术式。在此,我们回顾了我们在俯卧位下对直径大于1.5 cm的肾结石进行标准PCNL的初步经验,包括患者的结石清除率和并发症情况。

患者与方法

回顾性分析2020年9月至2023年9月期间24例行标准PCNL及气压弹道碎石术患者的记录。所有因直径大于1.5 cm的肾结石而接受标准PCNL的患者均纳入本研究。收集患者的人口统计学数据、手术指征、结石位置、结石大小、术后肾造瘘管放置情况、肾造瘘通道大小、并发症、手术时长、住院时长及结石清除情况,并对数据进行统计分析。

结果

共有24例患者接受了标准PCNL。患者的平均年龄为47.0±10.28岁(16例男性,8例女性;年龄范围:17 - 68岁)。胁腹疼痛是手术的主要指征。平均结石大小为2.5 cm(范围:1.6 - 3.3 cm)。平均Hounsfield单位为1248.2 HU(范围:927 - 1502 HU)。单次手术中,20例(83.3%)患者实现了100%结石清除。2例(8.3%)患者因术中出血和肾盂肾盏系统穿孔导致手术终止并需置入肾造瘘管,需进行第二次PCNL。另外2例(8.3%)患者结石移位且无法触及。1例(4.2%)患者因持续性尿漏住院10天,在置入双J支架管并给予抗生素治疗后尿漏最终停止。采用Clavien - Dindo分级系统对术后并发症进行分类。共有14例(58.3%)患者发生I级并发症,3例(12.5%)患者发生II级并发症,1例(4.2%)患者发生IIIa级并发症。

结论

PCNL是治疗大的肾结石的一种有效的微创技术。我们的初步经验表明,PCNL的并发症发生率在可接受范围内。

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