Kishimoto Kenji, Asai Shuji, Suzuki Mochihito, Sato Ryo, Hasegawa Junya, Ohno Yusuke, Terabe Kenya, Imagama Shiro
Department of Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Department of Orthopaedic Surgery, Nishio Municipal Hospital, Nishio, Japan.
Mod Rheumatol. 2025 Jul 5;35(4):744-752. doi: 10.1093/mr/roaf022.
This study aimed to examine relationships of the degree and level of spinal ankylosis with spinal mobility and functional impairment in patients with radiographic axial spondyloarthritis (r-axSpA) using computed tomography (CT).
This retrospective study involving 27 patients examined the number of fused intervertebral segments in the whole, cervical, thoracic, and lumbar spine using CT as a measure of spinal ankylosis, Bath Ankylosing Spondylitis Metrology Index (BASMI) as a measure of spinal mobility, and Bath Ankylosing Spondylitis Functional Index (BASFI) as a measure of functional impairment.
Significant positive correlations were found between both BASMI and BASFI and the number of fused intervertebral segments in the whole, cervical, thoracic, and lumbar spine. 'Tragus to wall distance', a BASMI item, was significantly positively correlated with the number of intervertebral segments in the lumbar spine (r = 0.46, P = .02). 'Looking over your shoulder', a BASFI item, was strongly negatively correlated with the number of fused intervertebral segments in the cervical spine (r = 0.804, P < .01).
The number of fused intervertebral segments was associated with impaired spinal mobility and functional impairment. Impaired spinal motion and functional impairment in daily living varied depending on the level of spinal ankylosis.
本研究旨在利用计算机断层扫描(CT)检查影像学轴向脊柱关节炎(r-axSpA)患者脊柱强直的程度和水平与脊柱活动度及功能障碍之间的关系。
这项回顾性研究纳入了27例患者,使用CT测量整个脊柱、颈椎、胸椎和腰椎融合的椎间节段数量,以此作为脊柱强直的指标;使用巴斯强直性脊柱炎测量指数(BASMI)作为脊柱活动度的指标;使用巴斯强直性脊柱炎功能指数(BASFI)作为功能障碍的指标。
发现BASMI和BASFI与整个脊柱、颈椎、胸椎和腰椎融合的椎间节段数量均呈显著正相关。BASMI项目“耳屏至墙距离”与腰椎的椎间节段数量呈显著正相关(r = 0.46,P = 0.02)。BASFI项目“扭头看身后”与颈椎融合的椎间节段数量呈强烈负相关(r = 0.804,P < 0.01)。
融合的椎间节段数量与脊柱活动度受损及功能障碍相关。脊柱运动受损和日常生活中的功能障碍因脊柱强直的水平而异。