Huang Yushu, Guo Dan, Hu Daixing, Yang Yaru, Deng Qin
Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University, No.76 Linjiang Road, Yu Zhong District, Chongqing, 400010, China.
Department of Breast and Thyroid Surgery, The Third Affiliated Hospital of Army Medical University (Daping Hospital), No.10 Changjiang Branch Road, Yu Zhong District, Chongqing, 400042, China.
BMC Endocr Disord. 2025 Mar 10;25(1):61. doi: 10.1186/s12902-025-01886-4.
To evaluate the frequency of erectile dysfunction in male patients who undergo thyroidectomy using the International Index of Erectile Function (IIEF-5), and explore possible risk factors.
163 male patients who undergo partial, unilateral or bilateral thyroidectomy between December 2021 and September 2022 were retrospectively studied. The IIEF-5 questionnaires were completed 6 and 12 months after surgery, and patients who reported erectile dysfunction (ED) before surgery were not included. Sociodemographic factors (age, education status, and employment status) and health behavior (smoking and alcohol consumption) were also recorded. The above factors and clinical data were included for statistical analysis.
Fifty-five patients underwent total thyroidectomy (TT), 67 underwent hemithyroidectomy (HT), and 41 underwent partial thyroidectomy (PT). Six months after surgery, 33 patients (60%) in the TT group, 38 (56.7%) patients in the HT group, and 11(26.8%) patients in the PT group reported ED. The lowest scores were observed in the TT group (TT: 19.22 ± 3.895, HT: 20.67 ± 2.836, PT: 21.98 ± 1.651, P < 0.05). At the 12-month postoperative visit, the mean IIEF-5 scores were better in the HT and PT groups and worse in the TT group (TT: 18.36 ± 4.335, HT: 21.40 ± 2.692, PT: 22.54 ± 1.206, P < 0.05). Binary logistic regression analysis revealed that age and extent of resection significantly affected the onset of postoperative ED.
Thyroidectomy, especially the total thyroidectomy, adversely affects erectile function. In addition to the operative procedure, age was also found to be significantly associated with postoperative ED.
使用国际勃起功能指数（IIEF-5）评估接受甲状腺切除术的男性患者勃起功能障碍的发生率，并探讨可能的危险因素。
回顾性研究2021年12月至2022年9月期间接受部分、单侧或双侧甲状腺切除术的163例男性患者。术后6个月和12个月完成IIEF-5问卷调查，术前报告有勃起功能障碍（ED）的患者不纳入研究。还记录了社会人口学因素（年龄、教育程度和就业状况）和健康行为（吸烟和饮酒）。将上述因素和临床数据纳入统计分析。
55例患者接受了全甲状腺切除术（TT），67例接受了半甲状腺切除术（HT），41例接受了部分甲状腺切除术（PT）。术后6个月，TT组33例患者（60%）、HT组38例患者（56.7%）、PT组11例患者（26.8%）报告有ED。TT组得分最低（TT：19.22±3.895，HT：20.67±2.836，PT：21.98±1.651，P<0.05）。术后12个月随访时，HT组和PT组的IIEF-5平均得分较好，TT组较差（TT：18.36±4.335，HT：21.40±2.692，PT：22.54±1.206，P<0.05）。二元逻辑回归分析显示，年龄和切除范围显著影响术后ED的发生。
甲状腺切除术，尤其是全甲状腺切除术，对勃起功能有不利影响。除手术操作外，还发现年龄与术后ED显著相关。
