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一名患有埃布斯坦畸形患者人工瓣膜心内膜炎的良好预后。

Favourable outcome of prosthetic valve endocarditis in a patient with an Ebstein anomaly.

作者信息

Lee-Jones Scott G, van der Westhuizen Stefan, Taljaard Johannes, Govender Nelesh P, Razack Rubina

机构信息

Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Division of Cardiothoracic Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

出版信息

S Afr J Infect Dis. 2025 Feb 11;40(1):699. doi: 10.4102/sajid.v40i1.699. eCollection 2025.

DOI:10.4102/sajid.v40i1.699
PMID:40060086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11886575/
Abstract

UNLABELLED

Fungal endocarditis is rare, challenging to diagnose and treat and associated with high mortality. We describe a case of endocarditis in a patient with Ebstein's anomaly with a favourable outcome.

CONTRIBUTION

We emphasise that surgical intervention with source control of the infective vegetation is still the mainstay of treatment and highlight the importance of submitting infected source material for histology, culture and molecular testing to identify the causative organism.

摘要

未加标注

真菌性心内膜炎罕见,诊断和治疗具有挑战性,且死亡率高。我们描述了一例患有埃布斯坦畸形的患者的心内膜炎病例,其预后良好。

贡献

我们强调,对感染性赘生物进行源头控制的手术干预仍是主要治疗方法,并强调提交感染源材料进行组织学、培养和分子检测以鉴定致病微生物的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/6b8b73e9841b/SAJID-40-699-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/da2e15dac40c/SAJID-40-699-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/11eee95f5523/SAJID-40-699-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/6b8b73e9841b/SAJID-40-699-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/da2e15dac40c/SAJID-40-699-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/11eee95f5523/SAJID-40-699-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6cd/11886575/6b8b73e9841b/SAJID-40-699-g003.jpg

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本文引用的文献

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Invasive fusariosis.侵袭性镰刀菌病。
Clin Microbiol Rev. 2023 Dec 20;36(4):e0015922. doi: 10.1128/cmr.00159-22. Epub 2023 Nov 8.
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Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management.真菌性心内膜炎:病理生理学、流行病学、临床表现、诊断和治疗。
Clin Microbiol Rev. 2023 Sep 21;36(3):e0001923. doi: 10.1128/cmr.00019-23. Epub 2023 Jul 13.
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The Impact of Corticosteroids on the Outcome of Fungal Disease: a Systematic Review and Meta-analysis.皮质类固醇对真菌病结局的影响:一项系统评价和荟萃分析。
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Narrative review of Ebstein's anomaly beyond childhood: Imaging, surgery, and future perspectives.儿童期后埃布斯坦畸形的叙述性综述:影像学、手术及未来展望
Cardiovasc Diagn Ther. 2021 Dec;11(6):1310-1323. doi: 10.21037/cdt-20-771.
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Causes of infective endocarditis in the Western Cape, South Africa: a prospective cohort study using a set protocol for organism detection and central decision making by an endocarditis team.南非西开普省感染性心内膜炎的病因:采用一套病原体检测方案和感染性心内膜炎专家组进行中心决策的前瞻性队列研究。
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Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology.罕见霉菌感染诊断与管理全球指南:欧洲医学真菌学联合会与国际人类与动物真菌学会及美国微生物学会合作发起
Lancet Infect Dis. 2021 Aug;21(8):e246-e257. doi: 10.1016/S1473-3099(20)30784-2. Epub 2021 Feb 16.
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Endocarditis by Fusarium keratoplasticum.角膜塑形镰刀菌引起的心内膜炎。
Mycopathologia. 2021 Mar;186(1):131-133. doi: 10.1007/s11046-020-00502-4. Epub 2020 Nov 3.
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Human fusariosis: An emerging infection that is difficult to treat.人类镰刀菌病:一种难以治疗的新兴感染。
Rev Soc Bras Med Trop. 2020;53:e20200013. doi: 10.1590/0037-8682-0013-2020. Epub 2020 Jun 1.
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