Programa de Pós-Graduação Stricto Sensu em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Programa de Pós-Graduação em Microbiologia Agrícola e do Ambiente, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Rev Soc Bras Med Trop. 2020;53:e20200013. doi: 10.1590/0037-8682-0013-2020. Epub 2020 Jun 1.
Fusarium spp. has been associated with a broad spectrum of emerging infections collectively termed fusariosis. This review includes articles published between 2005 and 2018 that describe the characteristics, clinical management, incidence, and emergence of these fungal infections. Fusarium solani and F. oxysporum are globally distributed and represent the most common complexes. Few therapeutic options exist due to intrinsic resistance, especially for the treatment of invasive fusariosis. Therefore, the use of drug combinations could be an important alternative for systemic antifungal resistance. Increase in the number of case reports on invasive fusariosis between 2005 and 2018 is evidence of the emergence of this fungal infection.
镰刀菌属与一系列新兴感染有关，统称为镰刀菌病。本综述包括 2005 年至 2018 年期间发表的描述这些真菌感染的特征、临床管理、发生率和出现的文章。茄病镰刀菌和尖孢镰刀菌在全球范围内分布，是最常见的菌属。由于固有耐药性，治疗选择有限，尤其是侵袭性镰刀菌病的治疗。因此，联合使用药物可能是治疗系统性抗真菌耐药的重要选择。2005 年至 2018 年期间侵袭性镰刀菌病的病例报告数量增加，证明了这种真菌感染的出现。
