Shah Akash A, Zukotynski Brian K, Kim Chohee, Shi Brendan Y, Lee Changhee, Devana Sai K, Upfill-Brown Alexander, Mayer Erik N, SooHoo Nelson F, Lee Christopher
Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Department of Artificial Intelligence, Chung-Ang University, Seoul, South Korea.
OTA Int. 2025 Mar 7;8(2):e364. doi: 10.1097/OI9.0000000000000364. eCollection 2025 Jun.
Prediction of nonhome discharge after open reduction internal fixation (ORIF) of distal femur fractures may facilitate earlier discharge planning, potentially decreasing costs and improving outcomes. We aim to develop algorithms predicting nonhome discharge and time to discharge after distal femur ORIF and identify features important for model performance.
This is a retrospective cohort study of adults in the American College of Surgeons National Surgical Quality Improvement Program database who underwent distal femur ORIF between 2010 and 2019. The primary outcome was nonhome discharge, and the secondary outcome was time to nonhome discharge. We developed logistic regression and machine learning models for prediction of nonhome discharge. We developed an ensemble machine learning-driven survival model to predict discharge within 3, 5, and 7 days.
Of the 5330 patients included, 3772 patients were discharged to either a skilled nursing facility or rehabilitation hospital after index ORIF. Of all tested models, the logistic regression algorithm was the best-performing model and well calibrated. The ensemble model predicts discharge within 3, 5, and 7 days with fair discrimination. The following features were the most important for model performance: inpatient status, American Society of Anesthesiology classification, preoperative functional status, wound status, medical comorbidities, age, body mass index, and preoperative laboratory values.
We report a well-calibrated algorithm that accurately predicts nonhome discharge after distal femur ORIF. In addition, we report an ensemble survival algorithm predicting time to nonhome discharge. Accurate preoperative prediction of discharge destination may facilitate earlier discharge, reducing the costs and complications associated with prolonged hospitalization.
预测股骨远端骨折切开复位内固定术(ORIF)后非回家出院情况,可能有助于更早地进行出院计划,潜在地降低成本并改善治疗结果。我们旨在开发预测股骨远端ORIF后非回家出院及出院时间的算法,并确定对模型性能重要的特征。
这是一项对美国外科医师学会国家外科质量改进计划数据库中2010年至2019年间接受股骨远端ORIF的成年人进行的回顾性队列研究。主要结局是非回家出院,次要结局是非回家出院时间。我们开发了逻辑回归和机器学习模型来预测非回家出院情况。我们开发了一种集成机器学习驱动的生存模型来预测3天、5天和7天内的出院情况。
在纳入的5330例患者中,3772例患者在初次ORIF后被送往专业护理机构或康复医院。在所有测试模型中,逻辑回归算法是表现最佳且校准良好的模型。集成模型对3天、5天和7天内出院情况的预测具有一定的区分度。以下特征对模型性能最为重要:住院状态、美国麻醉医师协会分级、术前功能状态、伤口状态、合并症、年龄、体重指数和术前实验室检查值。
我们报告了一种校准良好的算法,可准确预测股骨远端ORIF后的非回家出院情况。此外,我们报告了一种预测非回家出院时间的集成生存算法。术前准确预测出院目的地可能有助于更早出院,降低与延长住院相关的成本和并发症。