Cabrita André, Lisboa Gonçalves Pedro, Marques Catarina A
Cardiology Department, Unidade Local De Saúde São João, Porto, PRT.
Nephrology Department, Unidade Local De Saúde São João, Porto, PRT.
Cureus. 2025 Feb 7;17(2):e78662. doi: 10.7759/cureus.78662. eCollection 2025 Feb.
Ciprofloxacin is a widely used empiric antibiotic that may cause adverse reactions, including leukocytoclastic vasculitis (LCV). We present the case of a 51-year-old woman diagnosed with pyelonephritis, who developed cutaneous vasculitic lesions one day after ciprofloxacin administration. The differential diagnosis was broad and included autoimmune diseases, which were ruled out through extensive testing. A skin biopsy confirmed LCV. This rare drug-induced reaction was successfully managed by discontinuing ciprofloxacin, and the patient made a full recovery within five days without the need for corticosteroid treatment.
环丙沙星是一种广泛使用的经验性抗生素，可能会引起不良反应，包括白细胞破碎性血管炎（LCV）。我们报告一例51岁女性，被诊断为肾盂肾炎，在使用环丙沙星一天后出现皮肤血管炎性病变。鉴别诊断范围广泛，包括自身免疫性疾病，通过广泛检查已排除。皮肤活检确诊为白细胞破碎性血管炎。通过停用环丙沙星成功处理了这种罕见的药物诱导反应，患者在五天内完全康复，无需皮质类固醇治疗。
