Shilpashree H S, Sarapur Shriprasad
Department of Oral Medicine and Radiology, RKDF Dental College and Research Center, Bhopal, Madhya Pradesh, India.
J Pharmacol Pharmacother. 2012 Oct;3(4):339-41. doi: 10.4103/0976-500X.103696.
Ciprofloxacin is one of the most commonly used antibacterial agents with relatively few side effects. Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0.6%. One of the side effects of ciprofloxacin is erythema multiforme (EM). EM is an acute, self -limiting mucocutaneous hypersensitivity syndrome. It exhibits a diverse etiology, often recurs, has unusual clinical features and is of uncertain etiopathogenesis. It usually exhibits a distinctive skin or mucosal lesions that are characterized by combination of bullae, papules, macules or ulcers. It is most probably an immunologically mediated process. With the use of ciprofloxacin becoming more and more widespread, fatal complications of ciprofloxacin should be borne in mind. In this article we present a case of ciprofloxacin induced erythema multiforme in 40 year old woman.
环丙沙星是最常用的抗菌药物之一，副作用相对较少。环丙沙星报告的严重不良反应很少见，发生率为0.6%。环丙沙星的副作用之一是多形红斑（EM）。EM是一种急性、自限性的黏膜皮肤超敏综合征。它病因多样，常复发，具有不寻常的临床特征，病因发病机制尚不确定。它通常表现出独特的皮肤或黏膜病变，其特征为水疱、丘疹、斑疹或溃疡的组合。这很可能是一个免疫介导的过程。随着环丙沙星的使用越来越广泛，应牢记环丙沙星的致命并发症。在本文中，我们介绍了一名40岁女性因环丙沙星诱发多形红斑的病例。
