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基于生物心理社会模型的患者教育对全膝关节置换术后疼痛及疼痛相关危险因素的影响:一项回顾性倾向评分匹配研究

Effects of Biopsychosocial Model-Based Patient Education on Pain and Pain-Related Risk Factors After Total Knee Arthroplasty: A Retrospective Propensity Score-Matched Study.

作者信息

Nishimoto Junji, Deguchi Naoki, Tanaka Shigeharu, Inoue Yu, Tanaka Ryo

机构信息

Graduate School of Humanities and Social Sciences, Hiroshima University, Higashi-Hiroshima, JPN.

Department of Rehabilitation, Saitama Medical Center, Saitama Medical University, Kawagoe, JPN.

出版信息

Cureus. 2025 Feb 7;17(2):e78707. doi: 10.7759/cureus.78707. eCollection 2025 Feb.

Abstract

BACKGROUND

The impact of interventions based on a biopsychosocial (BPS) model, including components related to sleep and nutrition, on pain after total knee arthroplasty (TKA) remains unclear. The purpose of this study was to develop patient education (PE) based on the BPS model and to clarify its effects on pain after TKA.

METHODS

Participants were 121 patients who had undergone unilateral TKA for knee osteoarthritis. Patients who received usual physiotherapy (control group, n = 71) or usual physiotherapy plus PE (PE group, n = 50) were identified. The primary outcome was the change in Knee injury and Osteoarthritis Outcome Score (KOOS) pain score from baseline to three months post-TKA.

RESULTS

After propensity score matching, there was no statistically significant difference in the change in KOOS pain scores between the control groups and PE ( = 0.143, = 0.240). Regarding pain-related risk factors, the Central Sensitization Inventory ( = 0.041, = 0.238), Pittsburgh Sleep Quality Index ( = 0.040, = 0.239), and Pain Catastrophizing Scale ( = 0.004, = 0.334) scores improved statistically significantly more in the PE group than in the control group. Hospital Anxiety and Depression Scale (HADS)-Anxiety ( = 0.233, = 0.139), HADS-Depression ( = 0.333, = 0.113) were not statistically significantly different between the two groups.

CONCLUSIONS

A BPS model-based PE was developed, and its effects on pain and pain-related risk factors were clarified. PE may improve central sensitization, sleep disturbance, and pain catastrophizing, which are key pain-related risk factors.

摘要

背景

基于生物心理社会(BPS)模型的干预措施,包括与睡眠和营养相关的组成部分,对全膝关节置换术(TKA)后疼痛的影响尚不清楚。本研究的目的是基于BPS模型开展患者教育(PE),并阐明其对TKA后疼痛的影响。

方法

参与者为121例因膝关节骨关节炎接受单侧TKA的患者。确定接受常规物理治疗的患者(对照组,n = 71)或常规物理治疗加PE的患者(PE组,n = 50)。主要结局是从基线到TKA后三个月的膝关节损伤和骨关节炎结局评分(KOOS)疼痛评分的变化。

结果

倾向得分匹配后,对照组和PE组之间KOOS疼痛评分的变化无统计学显著差异(P = 0.143,95%CI = 0.240)。关于疼痛相关危险因素,PE组的中枢敏化量表(P = 0.041,95%CI = 0.238)、匹兹堡睡眠质量指数(P = 0.040,95%CI = 0.239)和疼痛灾难化量表(P = 0.004,95%CI = 0.334)评分改善在统计学上显著高于对照组。两组之间医院焦虑抑郁量表(HADS)-焦虑(P = 0.233,95%CI = 0.139)、HADS-抑郁(P = 0.333,95%CI = 0.113)无统计学显著差异。

结论

开发了基于BPS模型的PE,并阐明了其对疼痛及疼痛相关危险因素的影响。PE可能改善中枢敏化、睡眠障碍和疼痛灾难化,这些是关键的疼痛相关危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a05/11890546/89c8b2af8071/cureus-0017-00000078707-i01.jpg

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