Tsou Yung-An, Meng Nai-Hsin, Chang Wen-Dien, Hua Chun-Hung
Department of Otorhinolaryngology, China Medical University Hospital, No. 2, Yude Rd., North Dist, Taichung, 404327, Taiwan (R.O.C.).
Department of Physical Medicine and Rehabilitation, China Medical University, Taichung, Taiwan.
Sci Rep. 2025 Mar 10;15(1):8300. doi: 10.1038/s41598-025-87877-w.
This study aimed to assess the prevalence, severity, and progression of swallowing impairments in head and neck cancer (HNC) patients before and after treatment, using videofluoroscopy with the Modified Barium Swallow Impairment Profile (MBSImP) protocol. We retrospect survey 90 HNC patients was divided into rehabilitation (receiving swallowing rehabilitation) and non-rehabilitation groups. All participants underwent a videofluoroscopic swallowing study with MBSImP, the Penetration-Aspiration Scale (PAS), and the Swallowing Performance Status (SPS) scale, along with assessments using the EAT-10 and Functional Oral Intake Scale (FOIS) at baseline, and at 1 and 3 months post-treatment. In all patients, MBSImP, PAS, and FOIS scores worsened one month after therapy. However, patients who performed swallow exercises demonstrated statistically significant improvements in swallowing function (FOIS and EAT-10) and related quality of life (EAT-10, Reflux Symptom Index) after three months of rehabilitation. High aspiration rates (poor PAS scores) were observed in all HNC patients post-treatment, peaking at 1 month and persisting over time. Notably, the rehabilitation group showed recovery of swallowing function to pre-treatment levels. Dysphagia is a significant and enduring side effect that impacts the quality of life in HNC patients undergoing multimodal treatment. The study suggests that a proactive swallowing rehabilitation program can positively influence outcomes, particularly after 3 months of rehabilitation.
本研究旨在使用改良钡餐吞咽障碍评估量表（MBSImP）方案的视频透视检查法，评估头颈癌（HNC）患者治疗前后吞咽障碍的患病率、严重程度及进展情况。我们回顾性调查了90例HNC患者，将其分为康复组（接受吞咽康复治疗）和非康复组。所有参与者在基线时以及治疗后1个月和3个月均接受了使用MBSImP、渗透-误吸量表（PAS）和吞咽功能状态（SPS）量表的视频透视吞咽研究，同时使用EAT-10和功能性经口摄食量表（FOIS）进行评估。在所有患者中，治疗1个月后MBSImP、PAS和FOIS评分均恶化。然而，进行吞咽练习的患者在康复3个月后，吞咽功能（FOIS和EAT-10）及相关生活质量（EAT-10、反流症状指数）有统计学意义的改善。所有HNC患者治疗后均观察到高误吸率（PAS评分差），在1个月时达到峰值并随时间持续存在。值得注意的是，康复组吞咽功能恢复到了治疗前水平。吞咽困难是一种显著且持久的副作用，会影响接受多模式治疗的HNC患者的生活质量。该研究表明，积极的吞咽康复计划可对结果产生积极影响，尤其是在康复3个月后。
