Kimura Ion, Yasui Youichi, Kawano Hirotaka, Miyamoto Wataru
Department of Orthopaedic Surgery, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi, Tokyo, 173-8605, Japan.
J Med Case Rep. 2025 Mar 11;19(1):107. doi: 10.1186/s13256-025-05110-8.
Ankle arthrodesis is the most frequently performed salvage procedure for pyogenic arthritis. However, its failed fusion rate of approximately 15% has been considered problematic. Herein, we present a case of pyogenic ankle arthritis successfully treated via a two-stage surgical procedure on the basis of the induced membrane technique.
A 43-year-old Japanese male patient with alcoholic liver disease was referred to our institution. He complained of persistent ankle pain and local heat following osteosynthesis for a closed pilon fracture. Radiological examinations revealed massive destruction of the ankle joint. Cultures of samples obtained from the joint isolated Streptococcus viridans. On the basis of these findings, he was diagnosed with pyogenic ankle arthritis with osteomyelitis of the distal tibia and talus. We performed the two-stage procedure per the induced membrane technique. In the first stage, the necrotic and infected tissue was debrided, and a polymethylmethacrylate spacer was inserted into the bone defect. Intravenous antibiotics were administered for 1 week thereafter. In the second stage, which was performed 5 weeks after the first stage, the induced membrane was identified around the polymethylmethacrylate spacer and cut to remove the latter. Ankle arthrodesis was performed with three double-thread screws. Finally, the autologous cancellous bone graft harvested from the ipsilateral iliac crest was used to fill the bone defect. During the postoperative period, antibiotics were administered intravenously for 2 weeks. Blood examinations normalized 3 weeks after the second stage. The immobilization splint was maintained for 6 weeks, after which partial weight bearing was started, and 6 months after surgery, the patient returned to full weight bearing and walked confidently without ankle pain. Radiological evaluations performed 2 years after the second stage revealed complete consolidation, and he reported no pain while walking.
Ankle arthrodesis performed via the induced membrane technique not only successfully controlled infection, but also achieved complete bone union, enabling the preservation of ankle joint. This technique demonstrates its potential as a highly effective approach for treating pyogenic ankle arthritis.
踝关节融合术是化脓性关节炎最常实施的挽救性手术。然而,其约15%的融合失败率一直被认为是个问题。在此,我们报告一例基于诱导膜技术通过两阶段手术成功治疗的化脓性踝关节关节炎病例。
一名患有酒精性肝病的43岁日本男性患者被转诊至我院。他因闭合性Pilon骨折内固定术后持续踝关节疼痛和局部发热前来就诊。影像学检查显示踝关节大量破坏。从关节获取的样本培养分离出草绿色链球菌。基于这些发现,他被诊断为化脓性踝关节关节炎合并胫距骨骨髓炎。我们按照诱导膜技术实施了两阶段手术。在第一阶段,清除坏死和感染组织,并在骨缺损处插入聚甲基丙烯酸甲酯间隔物。此后静脉注射抗生素1周。在第一阶段术后5周进行第二阶段手术,在聚甲基丙烯酸甲酯间隔物周围识别出诱导膜并将其切开以取出间隔物。用三枚双螺纹螺钉进行踝关节融合术。最后,取自同侧髂嵴的自体松质骨移植用于填充骨缺损。术后静脉注射抗生素2周。第二阶段术后3周血液检查恢复正常。固定夹板维持6周,之后开始部分负重,术后6个月患者恢复完全负重且行走时无踝关节疼痛。第二阶段术后2年的影像学评估显示完全骨愈合,且他报告行走时无疼痛。
通过诱导膜技术进行的踝关节融合术不仅成功控制了感染,还实现了完全骨愈合,能够保留踝关节。该技术显示出其作为治疗化脓性踝关节关节炎的高效方法的潜力。