Mbapah Leslie Tasha, Tsague Midrelle Syntyche, Teuwafeu Denise Georges, Ngwanui Mbapah Tracy, Etaka Sandra Tabe, Jabbossung Fombo Enjeh, Pouekoua Brandon Carl Monika, Enanga Longsti Scarlet Tabot, Jantjie Taljaard
Triad Research Foundation (TRF), Buea, Cameroon.
Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Antimicrob Resist Infect Control. 2025 Mar 11;14(1):21. doi: 10.1186/s13756-025-01523-8.
Transmission-based precautions (TBP) and the proper use of personal protective equipment (PPE) are essential in preventing hospital-acquired infections (HAIs) and in controlling the emergence and spread of antimicrobial resistance (AMR). This study, therefore, aimed to determine healthcare providers' compliance with TBP and its determinants in healthcare settings to help curb the burden of HAIs and AMR.
This study was a cross-sectional, hospital-based research conducted among healthcare providers at four health facilities in the Fako division of Cameroon, from January 1 to May 31, 2024. A standardized observation form, adapted from the World Health Organization's checklist for hand hygiene practices, was used to assess compliance with Transmission-Based Precautions (TBP) among healthcare providers when interacting with patients known or suspected of having infectious pathogens. Multivariable logistic regression analysis was performed to identify factors independently associated with TBP compliance, with significance set at a p-value of less than 0.05.
The proportion of participants with good TBP compliance was 75.4% (95%CI: 67.4-82.2). Contact precaution compliance was 94.2%, while that for droplet /airborne was 12.8%. Factors independently associated with good TBP compliance were healthcare providers trained in IPC (aOR: 2.89, 95%CI: 1.16-7.22), the availability of PPE in the facility's departments (aOR: 6.00, 95%CI: 1.24-29.17), and working in the facility; Mount Mary Hospital (aOR: 22.47, 95%CI: 2.21-228.08).
Compliance with transmission-based precautions was suboptimal. The determinants of good compliance with TBP among healthcare providers were making PPE available in the facility and training healthcare providers on IPC. Tailored public health measures should be implemented to improve and sustain healthcare providers' compliance with TBP.
基于传播的预防措施（TBP）以及个人防护装备（PPE）的正确使用对于预防医院获得性感染（HAIs）以及控制抗菌药物耐药性（AMR）的出现和传播至关重要。因此，本研究旨在确定医疗机构中医疗服务提供者对TBP的依从性及其决定因素，以帮助减轻HAIs和AMR的负担。
本研究是一项基于医院的横断面研究，于2024年1月1日至5月31日在喀麦隆法科省四个卫生机构的医疗服务提供者中开展。一份根据世界卫生组织手部卫生实践检查表改编的标准化观察表，用于评估医疗服务提供者在与已知或疑似感染病原体的患者互动时对基于传播的预防措施（TBP）的依从性。进行多变量逻辑回归分析以确定与TBP依从性独立相关的因素，显著性设定为p值小于0.05。
TBP依从性良好的参与者比例为75.4%（95%CI：67.4 - 82.2）。接触预防措施的依从性为94.2%，而飞沫/空气传播预防措施的依从性为12.8%。与TBP依从性良好独立相关的因素包括接受过感染预防与控制（IPC）培训的医疗服务提供者（调整后比值比：2.89，95%CI：1.16 - 7.22）、医疗机构各科室PPE的可获得性（调整后比值比：6.00，95%CI：1.24 - 29.17）以及在玛丽山医院工作（调整后比值比：22.47，95%CI：2.21 - 228.08）。
基于传播的预防措施的依从性欠佳。医疗服务提供者中TBP良好依从性的决定因素是医疗机构提供PPE以及对医疗服务提供者进行IPC培训。应实施针对性的公共卫生措施以改善并维持医疗服务提供者对TBP的依从性。
