Vecchia Andres Agustin, Migliaro Giuseppe, Cioffi Paolo, Calderone Dario, Verolino Giuseppe
Cardiac Cath Lab, Città di Alessandria Institute, Via Moccagatta 30, 15121 Alessandria, Italy.
Unit of Cardiovascular Science, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 200, 00128 Rome, Italy.
Eur Heart J Case Rep. 2025 Mar 11;9(3):ytaf073. doi: 10.1093/ehjcr/ytaf073. eCollection 2025 Mar.
Sutureless bioprosthetic valves (SBVs) are engineered to enable a less invasive surgical valve replacement procedure in patients at high surgical risk. Valve degeneration is a relatively common occurrence across all types of surgical valves, including SBVs. Valve-in-valve (ViV) procedures are increasingly becoming the preferred treatment for many cases of valve degeneration due to their minimally invasive nature and favourable long-term outcomes. However, the specific structural characteristics of SBVs present challenges for ViV procedures, and the evidence on this subject remains limited.
A 91-year-old man was admitted to our hospital presenting with dyspnoea due to severe aortic regurgitation in a degenerated 3F Enable sutureless valve. Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) was successfully performed using a self-expanding Acurate Neo2 valve, yielding good haemodynamic results without overt interaction between the prosthesis. A 6-month follow-up echocardiogram confirmed excellent valve performance.
ViV-TAVI is a well-established treatment for bioprosthetic valve failure in high-risk patients. However, sutureless valve degeneration presents a challenging scenario for ViV procedures, with only a limited number of cases performed using the Acurate platform. In this case, we demonstrated the technical feasibility of ViV using the Acurate system in a less explored surgical sutureless bioprosthesis.
无缝合生物瓣膜(SBV)的设计目的是在手术风险高的患者中实现侵入性较小的外科瓣膜置换手术。瓣膜退变在包括SBV在内的所有类型的外科瓣膜中都相对常见。瓣中瓣(ViV)手术由于其微创性质和良好的长期效果,越来越成为许多瓣膜退变病例的首选治疗方法。然而,SBV的特定结构特征给ViV手术带来了挑战,关于这一主题的证据仍然有限。
一名91岁男性因一枚退变的3F Enable无缝合瓣膜严重主动脉瓣反流导致呼吸困难入住我院。使用自膨胀式Acurate Neo2瓣膜成功进行了瓣中瓣经导管主动脉瓣植入术(ViV-TAVI),血流动力学结果良好,假体之间无明显相互作用。术后6个月的超声心动图证实瓣膜功能极佳。
ViV-TAVI是高危患者生物瓣膜功能衰竭的成熟治疗方法。然而,无缝合瓣膜退变给ViV手术带来了具有挑战性的情况,使用Acurate平台进行的病例数量有限。在本病例中,我们展示了在较少探索的外科无缝合生物假体中使用Acurate系统进行ViV的技术可行性。