Mondal Saikat, Kottawar Venkatesh, Parvin Sunitaj, DasMunshi Boudhayan, Banerjee Saurav, Begam Nazneen Nahar, Sengupta Mallika
Department of Medicine, All India Institute of Medical Sciences, Kalyani, India.
Department of Microbiology, All India Institute of Medical Sciences, Kalyani, India.
Infez Med. 2025 Mar 1;33(1):139-143. doi: 10.53854/liim-3301-14. eCollection 2025.
We report a rare clinical presentation of a 54-year-old male diagnosed with infective endocarditis caused by , a nutritionally variant streptococcus (NVS) characterized by unique growth requirements and high pathogenic potential. The patient presented with prolonged fever and residual hemiparesis following an ischemic stroke. Blood culture confirmed , and imaging identified vegetations on a bicuspid aortic valve. Despite prompt antibiotic therapy, the course was complicated by acute intraventricular hemorrhage (IVH) and hydrocephalus, culminating in a fatal outcome. This report underscores the pathogenic challenges posed by , highlights its catastrophic complications, and reviews its presentation and management in the context of existing literature and emphasizing the importance of prompt diagnosis, tailored antibiotic therapy, and vigilant monitoring.
我们报告了一例罕见的临床病例，一名54岁男性被诊断为感染性心内膜炎，由营养变异型链球菌（NVS）引起，该菌具有独特的生长需求和高致病潜力。患者在缺血性中风后出现持续发热和残留偏瘫。血培养确诊为该菌，影像学检查发现二尖瓣主动脉瓣上有赘生物。尽管及时进行了抗生素治疗，但病程仍因急性脑室内出血（IVH）和脑积水而复杂化，最终导致死亡。本报告强调了该菌所带来的致病挑战，突出了其灾难性并发症，并结合现有文献回顾了其临床表现及治疗，强调了及时诊断、针对性抗生素治疗和密切监测的重要性。
