提取的蛋白聚糖与残留蛋白聚糖在糖胺聚糖水平上的比较以及随衰老的变化。

Comparisons between extracted and residual proteoglycans on the glycosaminoglycan level and changes with ageing.

作者信息

Theocharis D A

出版信息

Int J Biochem. 1985;17(2):155-60. doi: 10.1016/0020-711x(85)90109-0.

Abstract

Sheep nasal cartilage from animals of five different ages were studied. Significant variations in the composition and on the extractability of the tissue occur with ageing. The ratio chondroitin sulphate to keratan sulphate in extracted and residual proteoglycans does not change in the same manner with ageing. The relative distribution of molecular sizes of keratan sulphate differs between extracted and residual proteoglycans. Hyaluronic acid and chondroitin sulphate appear homogeneous on the gel chromatography for all ages both in extracted and residual proteoglycans.

摘要

对来自五个不同年龄阶段动物的羊鼻软骨进行了研究。随着年龄增长，组织的组成和可提取性出现显著变化。提取的和残留的蛋白聚糖中硫酸软骨素与硫酸角质素的比例随年龄增长的变化方式不同。硫酸角质素分子大小的相对分布在提取的和残留的蛋白聚糖之间存在差异。透明质酸和硫酸软骨素在所有年龄段的提取的和残留的蛋白聚糖的凝胶色谱上均表现为均一。