Dietl J, Stoll P
Geburtshilfe Frauenheilkd. 1985 May;45(5):299-301. doi: 10.1055/s-2008-1036463.
This report describes the results of a feasibility study of detection endometrial carcinoma in a population of 256 women, age 45 and above (221 patients with abnormal bleeding, 35 asymptomatic women). All of the asymptomatic women had a negative endometrial cytology. The microscopic examination of the curettings of patients with abnormal bleeding was correlated to the endometrial cytology. 13 adenocarcinomas, 2 sarcomas, but only 3 of 8 adenomatous hyperplasias, 2 of 4 circumscribed adenocarcinomas and none of 2 high differentiated adenoakanthomas were predicted by the cytological examination. The endouterine cell sampling is only effective in exophytic or broad endophytic growing adenocarcinomas. For precancerous conditions or early cancerous changes is the endouterine cell sampling not quite accurate. The routine use of endometrial cytology from the uterine cavity area is apparently not justified for early detection of endometrial carcinomas.
本报告描述了一项针对256名45岁及以上女性(221例异常出血患者,35例无症状女性)进行子宫内膜癌检测的可行性研究结果。所有无症状女性的子宫内膜细胞学检查均为阴性。对异常出血患者刮宫组织的显微镜检查结果与子宫内膜细胞学检查结果进行了对比。细胞学检查预测出13例腺癌、2例肉瘤,但在8例腺瘤样增生中仅预测出3例,4例局限性腺癌中仅预测出2例,2例高分化腺棘皮癌均未被预测出。宫腔细胞采样仅对外生性或广泛内生性生长的腺癌有效。对于癌前病变或早期癌变,宫腔细胞采样不太准确。常规使用宫腔区域的子宫内膜细胞学检查用于早期检测子宫内膜癌显然不合理。