Yang Mingming, Liang Bin, Zhao Xin, Wang Yang, Xue Mingyuan, Song Qipeng, Wang Dan
School of Athletic Performance, Shanghai University of Sport, 399 Changhai Road, Shanghai, 200082, China.
Department of Orthopedics, Nanjing First Hospital, Nanjing, 210012, China.
BMC Musculoskelet Disord. 2025 Mar 12;26(1):247. doi: 10.1186/s12891-025-08424-2.
Patellar fracture surgeries are associated with subsequent atrophy and weakness in the muscles of the lower limb. Individualized blood flow restriction training is progressively being recognized as a potential technique for improving muscular hypertrophy and accompanying strength in participants recovering from surgery. This study aimed to investigate the overall feasibility and observational outcomes of individualized blood flow restriction training for participants recovering from patellar fracture surgery.
A 47-year-old male (Participant one, body mass: 65 kg, height: 1.75 m, body mass index: 21.2 kg/m, three months post-patellar fracture surgery) and a 28-year-old female (Participant two, body mass: 53 kg, height: 1.67 m, body mass index: 19.8 kg/m, three months post-patellar fracture surgery) performed straight leg raises and leg extensions with individualized blood flow restriction for six weeks. The blood supply to the leg with the patellar fracture was partially restricted using a thigh pressure cuff inflated to 60% of the limb occlusion pressure. Peak torque of knee extensor, rectus femoris cross-sectional area, rectus femoris stiffness, and Lysholm score were measured at baseline and post-training.
Compared to baseline, the post-training peak torque of the knee extensor, rectus femoris cross-sectional area, rectus femoris stiffness, and Lysholm score of participants one post-surgical leg increased by 48.2%, 7.9%, 7.9%, and 23 points, respectively; those of participant two increased by 134.7%, 6.8%, 14.2%, and 30 points, respectively.
The results showed that the individualized blood flow restriction training was feasible and suggested promising outcomes for participants after surgery. Further research with a large sample size is required to flesh out and generalize the training program.
The Nanjing First Hospital's ethics committee accepted the research before testing. The clinical test was documented with clinicaltrials.gov (NCT05371431, Registered 08-20-2020, prospectively registered).
髌骨骨折手术会导致下肢肌肉随后出现萎缩和无力。个体化血流限制训练逐渐被认为是一种潜在技术，可用于改善接受手术康复的参与者的肌肉肥大及相应力量。本研究旨在调查个体化血流限制训练对髌骨骨折手术后康复参与者的总体可行性和观察结果。
一名47岁男性（参与者一，体重：65千克，身高：1.75米，体重指数：21.2千克/米²，髌骨骨折手术后三个月）和一名28岁女性（参与者二，体重：53千克，身高：1.67米，体重指数：19.8千克/米²，髌骨骨折手术后三个月）进行了六周的直腿抬高和腿部伸展训练，并采用个体化血流限制。使用充气至肢体闭塞压60%的大腿压力袖带部分限制髌骨骨折侧腿部的血液供应。在基线和训练后测量膝伸肌的峰值扭矩、股直肌横截面积、股直肌僵硬度和Lysholm评分。
与基线相比，参与者一手术侧腿部训练后的膝伸肌峰值扭矩、股直肌横截面积、股直肌僵硬度和Lysholm评分分别增加了48.2%、7.9%、7.9%和23分；参与者二的相应指标分别增加了134.7%、6.8%、14.2%和30分。
结果表明，个体化血流限制训练是可行的，且对术后参与者显示出有前景的结果。需要进一步进行大样本研究以完善并推广该训练方案。
南京第一医院伦理委员会在测试前接受了该研究。临床试验在clinicaltrials.gov上进行了记录（NCT05371431，于2020年8月20日注册，前瞻性注册）。
